HomeSearch by AntimicrobialTrovafloxacin (Trovan)
Antimicrobial Name: Trovafloxacin (Trovan)
CAS Number: 147059-72-1
Type of Antibiotic: Quinolones->Fourth Generation
Origin: Chemical/Synthetic
Functional Category: Antibiotic
Molecular Weight: 416.353
Mechanism of Action: Trovafloxacin (Trovan) is a broad spectrum antibiotic that inhibits the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV.
Chemical Formula:

C20H15F3N4O3

Solubility:

12.3 mg/L

Melting point:

 225 - 228 °C

Comments:

Trovafloxacin (Trovan) is a broad spectrum antibiotic that inhibits the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV. It was withdrawn from the market due to the risk of hepatotoxicity. It had better gram-positive bacterial coverage and less gram-negative coverage than the previous fluoroquinolones.