HomeSearch by AntimicrobialCefotaxime (Cephotaxime, Claforan)
Antimicrobial Name: Cefotaxime (Cephotaxime, Claforan)
CAS Number: 63527-52-6
Type of Antibiotic: Cephalosporins->Third Generation
Origin: Semi-synthetic
Functional Category: Antibiotic
Molecular Weight: 455.47
Mechanism of Action: The bactericidal activity of cefotaxime results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs). Cefotaxime shows high affinity for penicillin-binding proteins in the cell wall including PBP Ib and PBP III.
Chemical Formula:

C16H17N5O7S2

Solubility:

512 µg/ml in water

Melting point:

167-171°C

Comments:

Cefotaxime (Cephotaxime, Claforan) is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria.