HomeSearch by AntimicrobialMezlocillin (Mezlin)
Antimicrobial Name: Mezlocillin (Mezlin)
CAS Number: 51481-65-3
Type of Antibiotic: Penicillins
Origin: Semi-synthetic
Functional Category: Antibiotic
Molecular Weight: 539.584
Mechanism of Action: By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, mezlocillin inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that mezlocillin interferes with an autolysin inhibitor.
Chemical Formula:


Melting point:

170 °C (dec)


Mezlocillin (Mezlin) is a broad-spectrum penicillin antibiotic. It is active against both Gram-negative and some Gram-positive bacteria. Unlike most other extended spectrum penicillins, it is excreted by the liver, therefore it is useful for biliary tract infections, such as ascending colangitis.