HomeSearch by AntimicrobialMoxifloxacin (BAY 12-8039, Avelox)
Antimicrobial Name: Moxifloxacin (BAY 12-8039, Avelox)
CAS Number: 354812-41-2
Type of Antibiotic: Quinolones->Third Generation
Origin: Chemical/Synthetic
Functional Category: Antibiotic
Molecular Weight: 401.431
Mechanism of Action: The bactericidal action of moxifloxacin results from inhibition of the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV. DNA gyrase is an essential enzyme that is involved in the replication, transcription and repair of bacterial DNA. Topoisomerase IV is an enzyme known to play a key role in the partitioning of the chromosomal DNA during bacterial cell division.
Chemical Formula:



20 mg/ml in water

2 mg/ml in EtOH

5 µg/ml in 2-proponal

1 mg/ml in Acetone

Melting point:

203 - 208 °C  (dec)


Moxifloxacin (BAY 12-8039, Avelox) is a fourth-generation synthetic fluoroquinolone antibacterial agent developed by Bayer AG (initially called BAY 12-8039). It is marketed worldwide (as the hydrochloride) for oral treatment. In most countries, the drug is also available in parenteral form for intravenous infusion. Moxifloxacin is also sold in an ophthalmic solution (eye drops)  for the treatment of conjunctivitis (pink eye).