| Microorganism |
MIC50
(μg/ml) |
MIC90
(μg/ml) |
Range
(μg/ml) |
Antimicrobial |
Reference |
| Streptococcus pneumonia (Park I) |
- |
- |
0.03 － ? |
LY 191145  |
51 |
| Streptococcus pneumonia (Park I) |
- |
- |
0.13 － ? |
Chloroeremomycin (LY264826, A-82846B) |
51 |
| Streptococcus pneumonia (Park I) |
- |
- |
0.13 － ? |
Teicoplanin (Targocid) |
51 |
| Streptococcus pneumonia (Park I) |
- |
- |
0.5 － ? |
Vancomycin (Vancocyn, Lyphocin) |
51 |
| Streptococcus pneumonia (pbp2x and pbp2b or pbp1a and pbp2x genes abnormal + penicillin) |
0.008 |
16 |
0.002 － 0.031 |
Tebipenem (L-084) |
121 |
| Streptococcus pneumonia (pbp2x and pbp2b or pbp1a and pbp2x genes abnormal + penicillin) |
0.031 |
0.125 |
0.016 － 0.25 |
Faropenem |
121 |
| Streptococcus pneumonia (pbp2x and pbp2b or pbp1a and pbp2x genes abnormal + penicillin) |
0.25 |
0.25 |
0.063 － 0.5 |
Penicillin (Benzylpenicillin, Penicillin G, Bicillin C-R/L-A, Pfizerpen, Wycellin) |
121 |
| Streptococcus pneumonia (pbp2x and pbp2b or pbp1a and pbp2x genes abnormal + penicillin) |
0.5 |
1 |
0.063 － 2 |
Cefcapene |
121 |
| Streptococcus pneumonia (pbp2x and pbp2b or pbp1a and pbp2x genes abnormal + penicillin) |
0.5 |
1 |
0.063 － 2 |
Cefotaxime (Cephotaxime, Claforan) |
121 |
| Streptococcus pneumonia (pbp2x and pbp2b or pbp1a and pbp2x genes abnormal + penicillin) |
2 |
2 |
0.125 － 4 |
Cefdinir (Omnicef, Cefdiel) |
121 |
| Streptococcus pneumonia (pbp2x and pbp2b or pbp1a and pbp2x genes abnormal + penicillin) |
2 |
4 |
0.125 － 8 |
Cefpodoxime |
121 |
| Streptococcus pneumonia (pbp2x and pbp2b or pbp1a and pbp2x genes abnormal + penicillin) |
8 |
8 |
0.5 － 16 |
Cefaclor (Ceclor, Ceclor CD) |
121 |
| Streptococcus pneumonia (pbp2x and pbp2b or pbp1a and pbp2x genes abnormal + penicillin) |
- |
0.5 |
0.063 － 1 |
Cefditoren (Spectracef) |
121 |
| Streptococcus pneumonia (pbp2x and pbp2b or pbp1a and pbp2x genes abnormal + penicillin) |
- |
- |
0.063 － 1 |
Ampicillin (Omnipen) |
121 |
| Streptococcus pneumonia (pbp2x gene abnormal + penicillin-intermediate) |
0.008 |
0.016 |
0.008 － 0.063 |
Faropenem |
121 |
| Streptococcus pneumonia (pbp2x gene abnormal + penicillin-intermidiate) |
0.002 |
0.004 |
0.002 － 0.016 |
Tebipenem (L-084) |
121 |
| Streptococcus pneumonia (pbp2x gene abnormal + penicillin-intermidiate) |
0.063 |
0.063 |
0.031 － 0.25 |
Penicillin (Benzylpenicillin, Penicillin G, Bicillin C-R/L-A, Pfizerpen, Wycellin) |
121 |
| Streptococcus pneumonia (pbp2x gene abnormal + penicillin-intermidiate) |
0.063 |
0.125 |
0.016 － 0.25 |
Cefditoren (Spectracef) |
121 |
| Streptococcus pneumonia (pbp2x gene abnormal + penicillin-intermidiate) |
0.125 |
0.25 |
0.031 － 0.5 |
Cefotaxime (Cephotaxime, Claforan) |
121 |
| Streptococcus pneumonia (pbp2x gene abnormal + penicillin-intermidiate) |
0.125 |
0.5 |
0.031 － 0.5 |
Cefcapene |
121 |
| Streptococcus pneumonia (pbp2x gene abnormal + penicillin-intermidiate) |
0.5 |
1 |
0.063 － 2 |
Cefpodoxime |
121 |
| Streptococcus pneumonia (pbp2x gene abnormal + penicillin-intermidiate) |
1 |
1 |
0.5 － 8 |
Cefaclor (Ceclor, Ceclor CD) |
121 |
| Streptococcus pneumonia (pbp2x gene abnormal + penicillin-intermidiate) |
- |
0.063 |
0.031 － 0.5 |
Ampicillin (Omnipen) |
121 |
| Streptococcus pneumonia (pbp2x gene abnormal + penicillin-intermidiate) |
- |
- |
0.063 － 1 |
Cefdinir (Omnicef, Cefdiel) |
121 |
| Streptococcus pneumonia (pbpla, pbp2x, and pbp2b genes abnormal + penicillin-resistant) |
0.063 |
0.063 |
0.016 － 0.125 |
Tebipenem (L-084) |
121 |
| Streptococcus pneumonia (pbpla, pbp2x, and pbp2b genes abnormal + penicillin-resistant) |
0.25 |
0.5 |
0.063 － 1 |
Faropenem |
121 |
| Streptococcus pneumonia (pbpla, pbp2x, and pbp2b genes abnormal + penicillin-resistant) |
0.5 |
1 |
0.25 － 8 |
Cefcapene |
121 |
| Streptococcus pneumonia (pbpla, pbp2x, and pbp2b genes abnormal + penicillin-resistant) |
0.5 |
1 |
0.25 － 8 |
Cefditoren (Spectracef) |
121 |