| Antimicrobial Name： |
Terbinafine |
| CAS Number： |
91161-71-6 |
| Origin： |
Chemical/Synthetic |
| Functional Category： |
Antifungal |
| Molecular Weight： |
291.43 |
| Mechanism of Action： |
Terbinafine prevents conversion of squalene to lanosterol, ergosterol cannot be synthesized. This is thought to change cell membrane permeability, causing fungal cell lysis. |
| Chemical Formula： |
C21H25N |
| Solubility： |
Derivative Type: Hydrochloride: Freely sol in methanol, methylene chloride; sol in ethanol; slightly sol in water |
| Melting point： |
193 - 194 °C |
| Resistance Genes： |
yip1(?): terbinafine resistance locus protein YIP1, putative |
| Comments： |
Terbinafine is an oral antifungal drug (trade name Lamisil) used to treat cases of fungal nail disease. |