HomeSearch by AntimicrobialVoriconazole
Antimicrobial Name: Voriconazole
CAS Number: 137234-62-9
Origin: Chemical/Synthetic
Functional Category: Antifungal
Molecular Weight: 349.311
Mechanism of Action: Voriconazole binds and inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-alpha sterol demethylase. The inhibition of 14-alpha sterol demethylase results in a depletion of ergosterol in fungal cell membrane.
Chemical Formula:

C16H14F3N5O

Solubility:

Low

Melting point:

127-130°C

Comments:

Voriconazole is a triazole antifungal medication that is generally used to treat serious, invasive fungal infections. It is generally seen in patients who are immunocompromised, and include invasive candidiasis, invasive aspergillosis, and certain emerging fungal infections.