HomeSearch by AntimicrobialABT-492
Antimicrobial Name: ABT-492
Type of Antibiotic: Quinolones->Others
Functional Category: Antibiotic, Other
Mechanism of Action: ABT-492 was a potent inhibitor of bacterial topoisomerases, and unlike the comparators, DNA gyrase and topoisomerase IV from either Staphylococcus aureus or Escherichia coli were almost equally sensitive to ABT-492. The profile of ABT-492 suggested that it may be a useful agent for the treatment of community-acquired respiratory tract infections, as well as infections of the urinary tract, bloodstream, and skin and skin structure and nosocomial lung infections.
Solubility:

128 µg/ml in H2O

Comments:

ABT-492 is a new quinolone.