Home › Search by Antimicrobial › Nitrofurantoin (Macrobid, Macrodantin, Furantoin)
Antimicrobial Name： Nitrofurantoin (Macrobid, Macrodantin, Furantoin)
CAS Number： 67-20-9
Type of Antibiotic： Other Antibiotics
Functional Category： Antibiotic
Molecular Weight： 238.16
Mechanism of Action： Nitrofurantoin (Macrobid, Macrodantin, Furantoin) inhibits bacterial acetyl-coenzyme A, interfering with the organism’s carbohydrate metabolism. The drug also can disrupt bacterial cell wall formation.
Chemical Formula：

C8H6N4O5
Solubility：

19.0 mg/100 ml in water at pH 7

 

51.0 mg/100 ml in acetone

510 mg/100 ml in acetone

8000 mg/100 ml in DMF

2.1 mg/100 ml in peanut oil

60 mg/100 ml in glycerol

1500 mg/100 ml in wpolyethylene glycol
Melting point：

270-272 °C
Comments：

Nitrofurantoin (Macrobid, Macrodantin, Furantoin) is an antibiotic which is usually used in treating urinary tract infection. Like many other drugs, it is often used against E. coli.