HomeSearch by AntimicrobialNitrofurantoin (Macrobid, Macrodantin, Furantoin)
Antimicrobial Name: Nitrofurantoin (Macrobid, Macrodantin, Furantoin)
CAS Number: 67-20-9
Type of Antibiotic: Other Antibiotics
Functional Category: Antibiotic
Molecular Weight: 238.16
Mechanism of Action: Nitrofurantoin (Macrobid, Macrodantin, Furantoin) inhibits bacterial acetyl-coenzyme A, interfering with the organism’s carbohydrate metabolism. The drug also can disrupt bacterial cell wall formation.
Chemical Formula:



19.0 mg/100 ml in water at pH 7


51.0 mg/100 ml in acetone

510 mg/100 ml in acetone

8000 mg/100 ml in DMF

2.1 mg/100 ml in peanut oil

60 mg/100 ml in glycerol

1500 mg/100 ml in wpolyethylene glycol

Melting point:

270-272 °C


Nitrofurantoin (Macrobid, Macrodantin, Furantoin) is an antibiotic which is usually used in treating urinary tract infection. Like many other drugs, it is often used against E. coli.