Home › Search by Antimicrobial › Oxacillin (Prostaphilin, Bactocil, Prostaphlin)
Antimicrobial Name： Oxacillin (Prostaphilin, Bactocil, Prostaphlin)
CAS Number： 66-79-5
Type of Antibiotic： Penicillins
Origin： Semi-synthetic
Functional Category： Antibiotic
Molecular Weight： 401.436
Mechanism of Action： By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, Oxacillin inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that Oxacillin interferes with an autolysin inhibitor.
Chemical Formula：

C19H19N3O5S
Solubility：

13.9 mg/L
Melting point：

177 - 183 °C
Resistance Genes：

tetA: tetracycline, oxytetracycline and oxacillin resistance gene

tetB: tetracycline, oxytetracycline and oxacillin resistance gene

fmtC: oxacillin resistance-related FmtC protein
Comments：

By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, Oxacillin inhibits the third and last stage of bacterial cell wall synthesis.