HomeSearch by AntimicrobialParomomycin (Humatin)
Antimicrobial Name: Paromomycin (Humatin)
CAS Number: 7542-37-2
Type of Antibiotic: Aminoglycosides
Origin: Fermentation
Functional Category: Antibiotic
Molecular Weight: 615.629
Chemical Formula:

C23H45N5O14

Solubility:

Soluble in water; moderately sol in methanol; sparingly sol in abs ethanol.

Resistance Genes:

aac3iii: Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

aac3vii: Aminoglycoside N-acetyltransferase, which modifies aminoglycosides by acetylation.

aph3ia: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

aph3ib: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

aph3ic: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

aph3iia

aph3iiia: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

aph3iva: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

aph3va: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

aph3vb: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

aph3via: Aminoglycoside O-phosphotransferase, which modifies aminoglycosides by phosphorylation.

Comments:

Paromomycin (Humatin) is an aminoglycoside antibiotic, first isolated from Streptomyces krestomuceticus in the 1950s.