HomeSearch by AntimicrobialDifluoroquinolone (PD 117596)
Antimicrobial Name: Difluoroquinolone (PD 117596)
Type of Antibiotic: Quinolones->Others
Functional Category: Antibiotic, Other
Molecular Weight: 349.337
Chemical Formula:

C17H17F2N3O3

Melting point:

290 - 292 °C

Resistance Genes:

blt: Major facilitator superfamily transporter. Multidrug resistance efflux pump.

bmr: Major facilitator superfamily transporter. Multidrug resistance efflux pump.

emea: Major facilitator superfamily transporter. Multidrug resistance efflux pump.

mexa: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

mexb: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

mexc: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

mexd: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump. 

mexe: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

mexf: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

mfpa: Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

oprj: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

oprm: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

oprn: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

qnra: Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

qnrb: Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

qnrs: Pentapeptide repeat family, which protects DNA gyrase from the inhibition of quinolones.

smea: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

smeb: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

smec: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

smed: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

smee: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

smef: Resistance-nodulation-cell division transporter system. Multidrug resistance efflux pump.

Comments:

Difluoroquinolone (PD 117596) is an aminopyrrolidine-substituted fluorocyclopropyl quinolone.