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RWJ-416457
RWJ-416457
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Mycoplasma pneumonia
16
32
16 - 32
189
Staphylococci (coagulase-negative + methicillin-resistant)
-
-
0.12 - 1
280
Staphylococci (coagulase-negative + methicillin-susceptible)
-
-
0.25 - 0.5
280
Staphylococci (coagulase-negative)
0.5
1
0.25 - 1
189
Staphylococci (methicillin-resistant)
0.5
1
0.25 - 1
189
Staphylococci (methicillin-susceptible)
0.5
0.5
0.25 - 1
189
Staphylococcus aureus
1
2
0.25 - 16
189
Staphylococcus aureus
(4280-0256 + methicillin-resistant)
-
-
4 - ?
280
Staphylococcus aureus
(B2 posttherapy + methicillin-resistant)
-
-
8 - ?
280
Staphylococcus aureus
(community-acquired + methicillin-resistant)
1
2
1 - 2
189
Staphylococcus aureus
(H0 4280-0257 + methicillin-resistant)
-
-
8 - ?
280
Staphylococcus aureus
(H0 4280-0258 + methicillin-resistant)
-
-
8 - ?
280
Staphylococcus aureus
(H0 4536-0367 + methicillin-resistant)
-
-
2 - ?
280
Staphylococcus aureus
(H0 4536-0368 + methicillin-resistant)
-
-
8 - ?
280
Staphylococcus aureus
(linezolid-resistant + methicillin-resistant)
-
-
4 - 16
189
Staphylococcus aureus
(linezolid-susceptible + methicillin-resistant)
1
2
0.25 - 4
189
Staphylococcus aureus
(methicillin-resistant + vancomycin-intermediate)
0.5
2
0.25 - 2
189
Staphylococcus aureus
(methicillin-resistant)
-
-
0.12 - 1
280
Staphylococcus aureus
(methicillin-susceptible)
1
2
0.5 - 4
189
Staphylococcus aureus
(methicillin-susceptible)
-
-
0.25 - 1
280
Staphylococcus aureus
(RN4220 Δmut(S))
-
-
0.5 - ?
280
Staphylococcus aureus
(RN4220)
-
-
0.5 - ?
280
Staphylococcus aureus
(ST/02/2121)
-
-
1 - ?
280
Streptococcus pneumonia
0.5
0.5
0.06 - 1
189
Streptococcus pneumonia
(fluoroquinolone-resistant)
0.5
0.5
0.06 - 1
189
Streptococcus pneumonia
(macrolide-resistant)
0.5
0.5
0.25 - 1
189
Streptococcus pneumonia
(penicillin-resistant)
0.5
0.5
0.25 - 1
189
Streptococcus pyogenes
(macrolide-resistant)
0.5
0.5
0.25 - 0.5
189
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