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Finafloxacin
Finafloxacin
more info
Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Escherichia coli
(WT-3-M21 (gyr(A)[S83L] gyr(A)[D87G], lacks par(C), + CAMHB + pH 5.8)
-
-
8 - ?
1045
Escherichia coli
(WT-3-M21 (gyr(A)[S83L] gyr(A)[D87G], lacks par(C), + CAMHB + pH 7.2)
-
-
64 - ?
1045
Escherichia coli
(WT-3-M4 (gyr(A)[S83L] gyr(A)[D87G] par(C)[S80I]) + CAMHB + pH 5.8)
-
-
16 - ?
1045
Escherichia coli
(WT-3-M4 (gyr(A)[S83L] gyr(A)[D87G] par(C)[S80I]) + CAMHB + pH 7.2)
-
-
128 - ?
1045
Escherichia coli
(WT-4-M2-1 (lacks gyr(A), par(C)[S80I]) + CAMHB + pH 5.8)
-
-
0.015 - ?
1045
Escherichia coli
(WT-4-M2-1 (lacks gyr(A), par(C)[S80I]) + CAMHB + pH 7.2)
-
-
0.25 - ?
1045
Klebsiella pneumonia
(20 SHV-27 TEM + ESBL + CAMHB + pH 5.8)
-
-
4 - ?
1045
Klebsiella pneumonia
(20 SHV-27 TEM + ESBL + CAMHB + pH 7.2)
-
-
32 - ?
1045
Klebsiella pneumonia
(ATCC 13883 + CAMHB + pH 5.8)
-
-
0.015 - ?
1045
Klebsiella pneumonia
(ATCC 13883 + CAMHB + pH 7.2)
-
-
0.6 - ?
1045
Klebsiella pneumonia
(ATCC 700603 + ESBL + CAMHB + pH 5.8)
-
-
1 - ?
1045
Klebsiella pneumonia
(ATCC 700603 + ESBL + CAMHB + pH 7.2)
-
-
4 - ?
1045
Proteus mirabilis
(ATCC 9240 + CAMHB + pH 5.8)
-
-
0.25 - ?
1045
Proteus mirabilis
(ATCC 9240 + CAMHB + pH 7.2)
-
-
0.5 - ?
1045
Pseudomonas aeruginosa
(ATCC 10145 + CAMHB + pH 5.8)
-
-
1 - ?
1045
Pseudomonas aeruginosa
(ATCC 10145 + CAMHB + pH 7.2)
-
-
4 - ?
1045
Serratia marcescens
(ATCC 13880 + CAMHB + pH 5.8)
-
-
0.5 - ?
1045
Serratia marcescens
(ATCC 13880 + CAMHB + pH 7.2)
-
-
2 - ?
1045
Staphylococcus aureus
(103-17 (grl(A)[S80F] grl(A)[E84V] gyr(A)[S84L]) + CAMHB + pH 5.8)
-
-
4 - ?
1045
Staphylococcus aureus
(103-17 (grl(A)[S80F] grl(A)[E84V] gyr(A)[S84L]) + CAMHB + pH 7.2)
-
-
8 - ?
1045
Staphylococcus aureus
(104-13 (grl(A)[S80F] gyr(A)[S84L]) + CAMHB + pH 5.8)
-
-
1 - ?
1045
Staphylococcus aureus
(104-13 (grl(A)[S80F] gyr(A)[S84L]) + CAMHB + pH 7.2)
-
-
2 - ?
1045
Staphylococcus aureus
(105-11 (grl(A)[S80F] gyr(A)[S84A]) + CAMHB + pH 5.8)
-
-
0.5 - ?
1045
Staphylococcus aureus
(105-11 (grl(A)[S80F] gyr(A)[S84A]) + CAMHB + pH 7.2)
-
-
1 - ?
1045
Staphylococcus aureus
(ATCC 12600 + methicillin-susceptible + CAMHB + pH 5.8)
-
-
0.015 - ?
1045
Staphylococcus aureus
(ATCC 12600 + methicillin-susceptible + CAMHB + pH 7.2)
-
-
0.25 - ?
1045
Staphylococcus aureus
(ATCC 29213 + methicillin-susceptible + CAMHB + pH 5.8)
-
-
0.125 - ?
1045
Staphylococcus aureus
(ATCC 29213 + methicillin-susceptible + CAMHB + pH 7.2)
-
-
0.25 - ?
1045
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