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Linezolid (PNU-100766, U-100766, Zyvox)
Linezolid (PNU-100766, U-100766, Zyvox)
more info
Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Mycobacterium smegmatis
(C4 + linezolid-susceptible)
-
-
64 - ?
716
Mycobacterium smegmatis
(C5 + linezolid-susceptible)
-
-
4 - 8
716
Mycobacterium smegmatis
(C6 + linezolid-susceptible)
-
-
4 - 8
716
Mycobacterium smegmatis
(C7 + linezolid-susceptible)
-
-
64 - 128
716
Mycobacterium smegmatis
(G2447U)
-
-
>8 - ?
614
Mycobacterium smegmatis
(mc2155 SMR5 + linezolid-susceptible)
-
-
1 - ?
716
Mycobacterium smegmatis
(R1-rrl2446T)
-
-
64 - ?
716
Mycobacterium smegmatis
(R2-rrl2447T)
-
-
64 - 128
716
Mycobacterium smegmatis
(rrnB::aph + linezolid-susceptible)
-
-
1 - ?
716
Mycobacterium smegmatis
(U2504G)
-
-
8 - ?
614
Mycobacterium tuberculosis
0.5
1
? - ?
306
Mycobacterium tuberculosis
1
64
? - ?
1084
Mycobacterium tuberculosis
32
64
? - ?
1084
Mycobacterium tuberculosis
-
-
≤0.125 - ?
20
Mycobacterium tuberculosis
-
-
0.5 - 1
1080
Mycobacterium tuberculosis
(isoniazid-resistant + rifampicin-resistant)
4
64
0.125 - 64
335
Mycobacterium vaccae
(ATCC 15483)
-
-
1 - ?
1084
Mycobacterium xenopi
(ATCC 19970)
-
-
≤0.125 - ?
1084
Mycobacterium xenopi
(clinical isolate)
-
-
2 - ?
1084
Mycoplasma pneumonia
>64
>64
64 - >64
189
Nocardia brasiliensis
1
2
0.5 - 4
504
Parvimonas micra
1
3
0.125 - 3
1452
Peptoniphilus asaccharolyticus
0.5
1
0.5 - 1
1457
Peptoniphilus gorbachii
-
-
0.75 - 1.5
1452
Peptoniphilus harei
0.75
1.5
0.5 - 2
1452
Peptoniphilus ivorii
-
-
0.19 - 2
1452
Peptoniphilus lacrimalis
-
-
0.19 - 2
1452
Peptoniphilus octavius
-
-
0.75 - ?
1452
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