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Linezolid (PNU-100766, U-100766, Zyvox)
Linezolid (PNU-100766, U-100766, Zyvox)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Staphylococcus aureus
(vancomycin-intermediate)
-
-
1 - 2
726
Staphylococcus aureus
(vancomycin-intermediate)
-
-
2 - ?
106
Staphylococcus aureus
(vancomycin-intermediate)
-
-
2 - ?
517
Staphylococcus aureus
(vancomycin-intermediate-susceptible)
2
4
0.4 - 8
1060
Staphylococcus aureus
(vancomycin-intermediate-susceptible)
-
-
1 - 2
7
Staphylococcus aureus
(vancomycin-resistant)
2
-
1 - 2
1130
Staphylococcus aureus
(vancomycin-resistant)
-
2
? - ?
1358
Staphylococcus aureus
(vancomycin-resistant)
-
-
2 - ?
57
Staphylococcus aureus
(vancomycin-susceptible + Michigan strain)
-
-
1 - ?
273
Staphylococcus aureus
(vancomycin-susceptible + Pennsylvania strain)
-
-
2 - ?
273
Staphylococcus aureus
(VSAU6011)
-
-
1 - ?
621
Staphylococcus aureus
(VSAU6012)
-
-
1 - ?
621
Staphylococcus aureus
(VSAU6013)
-
-
2 - ?
621
Staphylococcus aureus
(VSAU6014)
-
-
1 - ?
621
Staphylococcus auricularis
1
1
0.12 - 2
472
Staphylococcus auricularis
(coagulase-negative + mupirocin-resistant)
0.5
1
0.25 - 2
592
Staphylococcus auricularis
(coagulase-negative + mupirocin-susceptible + oxacillin-susceptible)
1
2
0.25 - 2
592
Staphylococcus auricularis
(coagulase-negative + oxacillin-resistant)
0.5
1
0.25 - 2
592
Staphylococcus capitis
1
1
0.12 - 2
472
Staphylococcus capitis
(coagulase-negative + mupirocin-resistant)
0.5
1
0.25 - 2
592
Staphylococcus capitis
(coagulase-negative + mupirocin-susceptible + oxacillin-susceptible)
1
2
0.25 - 2
592
Staphylococcus capitis
(coagulase-negative + oxacillin-resistant)
0.5
1
0.25 - 2
592
Staphylococcus capitis
(coagulase-negative)
0.25
0.5
0.125 - 1
497
Staphylococcus chromogenes
(coagulase-negative)
0.25
0.5
0.125 - 1
497
Staphylococcus cohnii
1
1
0.12 - 2
472
Staphylococcus epidermidis
1
1
0.12 - 2
472
Staphylococcus epidermidis
-
-
1 - ?
20
Staphylococcus epidermidis
(887E + methicillin-resistant)
-
-
1 - ?
224
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