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Linezolid (PNU-100766, U-100766, Zyvox)
Linezolid (PNU-100766, U-100766, Zyvox)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Streptococcus pneumonia
(CDC 1293)
-
-
1000 - ?
373
Streptococcus pneumonia
(CDC 1325)
-
-
500 - ?
373
Streptococcus pneumonia
(CDC 1396)
-
-
1000 - ?
373
Streptococcus pneumonia
(CDC 141)
-
-
1000 - ?
373
Streptococcus pneumonia
(CDC 145)
-
-
1000 - ?
373
Streptococcus pneumonia
(CDC 146)
-
-
1000 - ?
373
Streptococcus pneumonia
(CDC 673)
-
-
1000 - ?
373
Streptococcus pneumonia
(CHM-11 + penicillin-resistant)
-
-
1 - ?
269
Streptococcus pneumonia
(erythromycin-resistant)
2
2
1 - 2
35
Streptococcus pneumonia
(Europe + erythromycin-resistant)
1
2
? - ?
306
Streptococcus pneumonia
(Europe + penicillin-resistant)
0.5
1
? - ?
306
Streptococcus pneumonia
(Europe + penicillin-susceptible)
0.5
1
? - ?
306
Streptococcus pneumonia
(fluoroquinolone-resistant)
0.5
1
0.5 - 2
189
Streptococcus pneumonia
(macrolide-resistant)
1
1
0.5 - 2
189
Streptococcus pneumonia
(macrolide-resistant)
-
-
0.5 - 2
49
Streptococcus pneumonia
(multidrug-resistant)
0.5
1
<0.25 - 1
1060
Streptococcus pneumonia
(North America + chloramphenicol-resistant)
0.25
1
? - ?
306
Streptococcus pneumonia
(North America + clindamycin-resistant)
0.5
1
? - ?
306
Streptococcus pneumonia
(North America + erm(B))
0.5
1
? - ?
306
Streptococcus pneumonia
(North America + mef(A))
0.5
1
? - ?
306
Streptococcus pneumonia
(North America + penicillin-intermediate)
0.75
1
? - ?
306
Streptococcus pneumonia
(North America + penicillin-resistant)
0.75
1
? - ?
306
Streptococcus pneumonia
(North America + penicillin-susceptible)
0.75
1
? - ?
306
Streptococcus pneumonia
(North America + tetracycline-resistant)
0.5
1
? - ?
306
Streptococcus pneumonia
(penicillin-intermediate)
0.5
1
? - ?
36
Streptococcus pneumonia
(penicillin-intermediate)
1
1
0.5 - 2
115
Streptococcus pneumonia
(penicillin-intermediate)
1
1
0.5 - 2
73
Streptococcus pneumonia
(penicillin-intermediate)
-
1
? - ?
1358
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