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Minocycline (Minocycline hydrochloride, Minocin)
Minocycline (Minocycline hydrochloride, Minocin)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Staphylococcus aureus
(methicillin-resistant)
0.25
0.5
≤0.25 - >8
42
Staphylococcus aureus
(methicillin-resistant)
0.25
0.5
≤0.25 - >=16
475
Staphylococcus aureus
(methicillin-resistant)
0.25
1
? - ?
36
Staphylococcus aureus
(methicillin-resistant)
1
8
0.25 - 8
410
Staphylococcus aureus
(methicillin-resistant)
-
-
8 - ?
257
Staphylococcus aureus
(methicillin-susceptible)
0.12
0.12
0.06 - 8
604
Staphylococcus aureus
(methicillin-susceptible)
≤0.25
≤0.25
≤0.25 - 8
475
Staphylococcus aureus
(methicillin-susceptible)
0.25
0.5
? - ?
36
Staphylococcus aureus
(methicillin-susceptible)
0.5
2
0.5 - 16
410
Staphylococcus aureus
(methicillin-susceptible)
-
-
0.25 - ?
257
Staphylococcus aureus
(oxacillin-resistant)
0.12
2
≤0.06 - 8
462
Staphylococcus aureus
(oxacillin-resistant)
0.25
0.25
0.06 - 8
476
Staphylococcus aureus
(oxacillin-susceptible)
0.06
0.12
≤0.06 - 0.25
462
Staphylococcus aureus
(oxacillin-susceptible)
0.12
0.12
0.06 - 8
476
Staphylococcus aureus
(Smith + methicillin-susceptible)
-
-
0.063 - ?
397
Staphylococcus aureus
(tet(K))
-
-
2 - ?
47
Staphylococcus aureus
(tet(M))
-
-
64 - ?
47
Staphylococcus aureus
(tetracycline-susceptible)
-
-
2 - ?
47
Staphylococcus aureus
(vancomycin-intermediate)
-
-
16 - ?
476
Staphylococcus aureus
(WIS-2)
-
-
0.06 - ?
34
Staphylococcus epidermidis
0.5
1
0.06 - 1
37
Staphylococcus epidermidis
-
0.5
≤0.015 - 2
37
Staphylococcus epidermidis
(ATCC 12228)
-
-
0.125 - ?
397
Staphylococcus epidermidis
(methicillin-resistant)
1
2
0.25 - 4
410
Staphylococcus epidermidis
(methicillin-susceptible)
0.5
1
0.25 - 1
410
Staphylococcus epidermidis
(oxacillin-resistant)
0.25
4
≤0.06 - 8
462
Staphylococcus epidermidis
(oxacillin-susceptible)
0.12
0.5
≤0.06 - 0.5
462
Staphylococcus haemolyticus
0.25
0.5
≤0.06 - 8
462
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