Microorganism |
MIC50 (μg/ml) |
MIC90 (μg/ml) |
Range (μg/ml) |
Antimicrobial |
Reference |
Escherichia coli (MH1) |
- |
- |
28 - ? |
Latarcin 3b |
637 |
Escherichia coli (MH1) |
- |
- |
>70 - ? |
Latarcin 6a |
637 |
Escherichia coli (MH1) |
- |
- |
>70 - ? |
Latarcin 7 |
637 |
Escherichia coli (MI (gyr(A)[S83L]) + CAMHB + pH 5.8) |
- |
- |
0.5 - ? |
Finafloxacin |
1045 |
Escherichia coli (MI (gyr(A)[S83L]) + CAMHB + pH 5.8) |
- |
- |
4 - ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
1045 |
Escherichia coli (MI (gyr(A)[S83L]) + CAMHB + pH 7.2) |
- |
- |
0.5 - ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
1045 |
Escherichia coli (MI (gyr(A)[S83L]) + CAMHB + pH 7.2) |
- |
- |
4 - ? |
Finafloxacin |
1045 |
Escherichia coli (MI-4 (gyr(A)[S83L] par(C)[S80I]) + CAMHB + pH 5.8) |
- |
- |
8 - ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
1045 |
Escherichia coli (MI-4 (gyr(A)[S83L] par(C)[S80I]) + CAMHB + pH 7.2) |
- |
- |
0.5 - ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
1045 |
Escherichia coli (MI-4 (gyr(A)[S83L] par(C)[S80I]) + CAMHB + pH 7.2) |
- |
- |
4 - ? |
Finafloxacin |
1045 |
Escherichia coli (MII (gyr(A)[S83L], lacks par(C), mar(R) deletion a + CAMHB + pH 5.8) |
- |
- |
2 - ? |
Finafloxacin |
1045 |
Escherichia coli (MII (gyr(A)[S83L], lacks par(C), mar(R) deletion a + CAMHB + pH 5.8) |
- |
- |
32 - ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
1045 |
Escherichia coli (MII (gyr(A)[S83L], lacks par(C), mar(R) deletion a + CAMHB + pH 7.2) |
- |
- |
2 - ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
1045 |
Escherichia coli (MII (gyr(A)[S83L], lacks par(C), mar(R) deletion a + CAMHB + pH 7.2) |
- |
- |
16 - ? |
Finafloxacin |
1045 |
Escherichia coli (MIII (gyr(A)[S83L] gyr(A)[D87G], par(C) [S80I], ma + CAMHB + pH 5.8) |
- |
- |
64 - ? |
Finafloxacin |
1045 |
Escherichia coli (MIII (gyr(A)[S83L] gyr(A)[D87G], par(C) [S80I], ma + CAMHB + pH 5.8) |
- |
- |
>128 - ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
1045 |
Escherichia coli (MIII (gyr(A)[S83L] gyr(A)[D87G], par(C) [S80I], ma + CAMHB + pH 7.2) |
- |
- |
128 - ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
1045 |
Escherichia coli (MIII (gyr(A)[S83L] gyr(A)[D87G], par(C) [S80I], ma + CAMHB + pH 7.2) |
- |
- |
>128 - ? |
Finafloxacin |
1045 |
Escherichia coli (minocycline-resistant) |
0.12 |
0.5 |
? - ? |
Tigecycline (GAR-936, Tigacyl) |
444 |
Escherichia coli (ML-35) |
- |
- |
0.5 - 1 |
P5 (D-Nle7) |
632 |
Escherichia coli (ML-35) |
- |
- |
0.5 - ? |
P4 (β-Ala7) |
632 |
Escherichia coli (ML-35) |
- |
- |
0.5 - ? |
P9 (Gly7) |
632 |
Escherichia coli (ML-35) |
- |
- |
1 - ? |
HBD-3 (Peptide) |
626 |
Escherichia coli (ML-35) |
- |
- |
1 - ? |
hcBD3 |
626 |
Escherichia coli (ML-35) |
- |
- |
1 - ? |
P1 (Aib7) |
631 |
Escherichia coli (ML-35) |
- |
- |
1 - ? |
P2 (Gly7) |
632 |
Escherichia coli (ML-35) |
- |
- |
1 - ? |
P3 (Pro7) |
632 |
Escherichia coli (ML-35) |
- |
- |
1 - ? |
P7 (Pst7) |
632 |