| Microorganism |
MIC50
(μg/ml) |
MIC90
(μg/ml) |
Range
(μg/ml) |
Antimicrobial |
Reference |
| Mycobacterium tuberculosis (ethambutol-resistant) |
0.01 |
- |
? － ? |
R207910 (TMC207)  |
1442 |
| Mycobacterium tuberculosis (first-Line-antituberculosis-drugs-resistant) |
0.5 |
1 |
≤0.125 － 8 |
Levofloxacin (Levaquin, Quixin) |
90 |
| Mycobacterium tuberculosis (first-Line-antituberculosis-drugs-resistant) |
1 |
2 |
≤0.125 － 8 |
Grepafloxacin (Raxar) |
90 |
| Mycobacterium tuberculosis (first-line-antituberculosis-drugs-resistant) |
1 |
2 |
0.5 － 8 |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
90 |
| Mycobacterium tuberculosis (first-Line-antituberculosis-drugs-resistant) |
1 |
2 |
0.5 － 16 |
Ofloxacin (Floxin) |
90 |
| Mycobacterium tuberculosis (first-Line-antituberculosis-drugs-resistant) |
8 |
8 |
2 － 64 |
Gemifloxacin |
90 |
| Mycobacterium tuberculosis (first-Line-antituberculosis-drugs-resistant) |
32 |
128 |
4 － >128 |
Trovafloxacin (Trovan) |
90 |
| Mycobacterium tuberculosis (first-Line-antituberculosis-drugs-susceptible) |
0.5 |
1 |
≤0.125 － 8 |
Levofloxacin (Levaquin, Quixin) |
90 |
| Mycobacterium tuberculosis (first-line-antituberculosis-drugs-susceptible) |
1 |
1 |
≤0.125 － 16 |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
90 |
| Mycobacterium tuberculosis (first-Line-antituberculosis-drugs-susceptible) |
1 |
1 |
≤0.125 － 16 |
Ofloxacin (Floxin) |
90 |
| Mycobacterium tuberculosis (first-Line-antituberculosis-drugs-susceptible) |
1 |
1 |
0.25 － 32 |
Grepafloxacin (Raxar) |
90 |
| Mycobacterium tuberculosis (first-Line-antituberculosis-drugs-susceptible) |
4 |
8 |
≤0.125 － 64 |
Gemifloxacin |
90 |
| Mycobacterium tuberculosis (first-Line-antituberculosis-drugs-susceptible) |
32 |
64 |
4 － >128 |
Trovafloxacin (Trovan) |
90 |
| Mycobacterium tuberculosis (fluoroquinolone-resistant) |
0.09 |
- |
0.06 － 0.12 |
R207910 (TMC207) |
1442 |
| Mycobacterium tuberculosis (GFPMA H37Ragfp) |
- |
- |
0.0125 － 0.05 |
Isoniazid (INH, Laniazid, Nydrazid, Rifamate) |
997 |
| Mycobacterium tuberculosis (GFPMA H37Ragfp) |
- |
- |
0.03 － 0.06 |
Rifampicin (Rifampin) |
997 |
| Mycobacterium tuberculosis (GFPMA H37Ragfp) |
- |
- |
0.5 － 1 |
Ofloxacin (Floxin) |
997 |
| Mycobacterium tuberculosis (GFPMA H37Ragfp) |
- |
- |
0.5 － 3.2 |
Clarithromycin (Biaxin) |
997 |
| Mycobacterium tuberculosis (GFPMA H37Ragfp) |
- |
- |
1.88 － ? |
Ethambutol (Myambutol) |
997 |
| Mycobacterium tuberculosis (GFPMA H37Ragfp) |
- |
- |
2.5 － ? |
Amikacin (Amikin) |
997 |
| Mycobacterium tuberculosis (GFPMA H37Ragfp) |
- |
- |
2.5 － ? |
Capreomycin (Capastat) |
997 |
| Mycobacterium tuberculosis (glycopeptide-resistant (A) + 94N) |
- |
- |
2 － ? |
Gatifloxacin (Tequin) |
999 |
| Mycobacterium tuberculosis (glycopeptide-resistant (A) + 94N) |
- |
- |
4 － ? |
Levofloxacin (Levaquin, Quixin) |
999 |
| Mycobacterium tuberculosis (glycopeptide-resistant (A) + 94N) |
- |
- |
4 － ? |
Moxifloxacin (BAY 12-8039, Avelox) |
999 |
| Mycobacterium tuberculosis (glycopeptide-resistant (A) + 94N) |
- |
- |
>8 － ? |
Ofloxacin (Floxin) |
999 |
| Mycobacterium tuberculosis (glycopeptide-resistant (A) + 94N) |
- |
- |
>32 － ? |
Enoxacin (Penetrex) |
999 |
| Mycobacterium tuberculosis (glycopeptide-resistant (A) + A90V) |
- |
- |
2 － ? |
Gatifloxacin (Tequin) |
999 |
| Mycobacterium tuberculosis (glycopeptide-resistant (A) + A90V) |
- |
- |
2 － ? |
Moxifloxacin (BAY 12-8039, Avelox) |
999 |