Microorganism |
MIC50 (μg/ml) |
MIC90 (μg/ml) |
Range (μg/ml) |
Antimicrobial |
Reference |
Staphylococci (coagulase-negative + methicillin-resistant) |
0.5 |
1 |
0.008 - 32 |
Gemifloxacin |
268 |
Staphylococci (coagulase-negative + methicillin-resistant) |
0.5 |
2 |
≤0.12 - 8 |
Tigecycline (GAR-936, Tigacyl) |
89 |
Staphylococci (coagulase-negative + methicillin-resistant) |
>0.5 |
>4 |
≤0.5 - >4 |
Clindamycin (Cleocin) |
73 |
Staphylococci (coagulase-negative + methicillin-resistant) |
0.5 |
16 |
0.25 - 64 |
Ofloxacin (Floxin) |
117 |
Staphylococci (coagulase-negative + methicillin-resistant) |
0.5 |
32 |
0.06 - >128 |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
117 |
Staphylococci (coagulase-negative + methicillin-resistant) |
>0.5 |
>128 |
≤0.12 - >128 |
Erythromycin (E-mycin, Ery-tab, Benzamycin) |
89 |
Staphylococci (coagulase-negative + methicillin-resistant) |
0.5 |
- |
0.06 - 2 |
LBM415 (NVP-PDF-713, VIC-10495) |
162 |
Staphylococci (coagulase-negative + methicillin-resistant) |
1 |
1 |
0.004 - 4 |
Daptomycin + 25 μg/ml Ca++ |
67 |
Staphylococci (coagulase-negative + methicillin-resistant) |
1 |
1 |
0.5 - 2 |
Tigecycline (GAR-936, Tigacyl) |
16 |
Staphylococci (coagulase-negative + methicillin-resistant) |
1 |
1.5 |
? - ? |
Ceftobiprole (Zeftera) |
935 |
Staphylococci (coagulase-negative + methicillin-resistant) |
1 |
2 |
0.015 - 32 |
Garenoxacin (T-3811, BMS-284756) |
268 |
Staphylococci (coagulase-negative + methicillin-resistant) |
1 |
2 |
≤0.016 - 8 |
Moxifloxacin (BAY 12-8039, Avelox) |
207 |
Staphylococci (coagulase-negative + methicillin-resistant) |
1 |
2 |
0.03 - 4 |
Gatifloxacin (Tequin) |
207 |
Staphylococci (coagulase-negative + methicillin-resistant) |
1 |
2 |
≤0.06 - 2 |
LBM415 (NVP-PDF-713, VIC-10495) |
207 |
Staphylococci (coagulase-negative + methicillin-resistant) |
1 |
2 |
0.06 - 4 |
Oritavancin (LY333328) |
162 |
Staphylococci (coagulase-negative + methicillin-resistant) |
1 |
2 |
0.25 - 2 |
Linezolid (PNU-100766, U-100766, Zyvox) |
109 |
Staphylococci (coagulase-negative + methicillin-resistant) |
1 |
2 |
0.25 - 4 |
LBM415 (NVP-PDF-713, VIC-10495) |
265 |
Staphylococci (coagulase-negative + methicillin-resistant) |
1 |
2 |
0.25 - 4 |
Vancomycin (Vancocyn, Lyphocin) |
67 |
Staphylococci (coagulase-negative + methicillin-resistant) |
1 |
2 |
0.5 - 2 |
Tigecycline (GAR-936, Tigacyl) |
175 |
Staphylococci (coagulase-negative + methicillin-resistant) |
1 |
2 |
0.5 - 4 |
Daptomycin (Cubicin) |
16 |
Staphylococci (coagulase-negative + methicillin-resistant) |
1 |
2 |
0.5 - 4 |
Vancomycin (Vancocyn, Lyphocin) |
73 |
Staphylococci (coagulase-negative + methicillin-resistant) |
1 |
2 |
1 - 2 |
Linezolid (PNU-100766, U-100766, Zyvox) |
72 |
Staphylococci (coagulase-negative + methicillin-resistant) |
1 |
2 |
1 - 4 |
Linezolid (PNU-100766, U-100766, Zyvox) |
207 |
Staphylococci (coagulase-negative + methicillin-resistant) |
1 |
2 |
? - ? |
Ceftobiprole (Zeftera) |
942 |
Staphylococci (coagulase-negative + methicillin-resistant) |
1 |
4 |
0.03 - 64 |
Moxifloxacin (BAY 12-8039, Avelox) |
268 |
Staphylococci (coagulase-negative + methicillin-resistant) |
>1 |
>16 |
? - ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
307 |
Staphylococci (coagulase-negative + methicillin-resistant) |
>1 |
>64 |
0.25 - >64 |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
178 |
Staphylococci (coagulase-negative + methicillin-resistant) |
1 |
64 |
0.25 - 64 |
Tetracycline (Sumycin, Achromycin V, Steclin) |
1464 |