| Microorganism |
MIC50
(μg/ml) |
MIC90
(μg/ml) |
Range
(μg/ml) |
Antimicrobial |
Reference |
| Streptococcus pneumonia (macrolide-resistant) |
1 |
1 |
0.5 － 2 |
Linezolid (PNU-100766, U-100766, Zyvox)  |
189 |
| Streptococcus pneumonia (macrolide-resistant) |
>4 |
>16 |
1 － >16 |
Erythromycin (E-mycin, Ery-tab, Benzamycin) |
189 |
| Streptococcus pneumonia (macrolide-resistant) |
- |
- |
≤0.015 － 0.5 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
49 |
| Streptococcus pneumonia (macrolide-resistant) |
- |
- |
0.1 － ? |
DC-159a |
268 |
| Streptococcus pneumonia (macrolide-resistant) |
- |
- |
0.1 － ? |
Moxifloxacin (BAY 12-8039, Avelox) |
268 |
| Streptococcus pneumonia (macrolide-resistant) |
- |
- |
0.285 － 1 |
Quinupristin/Dalfopristin (Synercid) |
49 |
| Streptococcus pneumonia (macrolide-resistant) |
- |
- |
0.5 － 2 |
Linezolid (PNU-100766, U-100766, Zyvox) |
49 |
| Streptococcus pneumonia (macrolide-resistant) |
- |
- |
1 － 8 |
Clindamycin (Cleocin) |
49 |
| Streptococcus pneumonia (macrolide-resistant) |
- |
- |
1 － >32 |
Rokitamycin |
49 |
| Streptococcus pneumonia (macrolide-resistant) |
- |
- |
32 － >32 |
Clarithromycin (Biaxin) |
49 |
| Streptococcus pneumonia (macrolide-resistant) |
- |
- |
>32 － ? |
Roxithromycin |
49 |
| Streptococcus pneumonia (macrolide-resistant) |
- |
- |
>64 － ? |
Azithromycin (Zithromax, Sumamed, Zitrocin) |
49 |
| Streptococcus pneumonia (macrolide-resistant) |
- |
- |
>64 － ? |
Erythromycin (E-mycin, Ery-tab, Benzamycin) |
49 |
| Streptococcus pneumonia (macrolide-susceptible) |
0.001 |
0.002 |
≤0.0005 － 0.004 |
Cethromycin (ABT-773) |
1111 |
| Streptococcus pneumonia (macrolide-susceptible) |
0.001 |
0.004 |
<0.001 － 0.008 |
Cethromycin (ABT-773) |
15 |
| Streptococcus pneumonia (macrolide-susceptible) |
0.004 |
0.008 |
≤0.0005 － 0.015 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
1111 |
| Streptococcus pneumonia (macrolide-susceptible) |
0.015 |
0.015 |
≤0.015 － 0.03 |
Cethromycin (ABT-773) |
236 |
| Streptococcus pneumonia (macrolide-susceptible) |
0.015 |
0.015 |
≤0.015 － 0.5 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
236 |
| Streptococcus pneumonia (macrolide-susceptible) |
0.015 |
0.03 |
0.002 － 0.06 |
Clarithromycin (Biaxin) |
15 |
| Streptococcus pneumonia (macrolide-susceptible) |
0.03 |
0.03 |
0.002 － 0.06 |
Erythromycin (E-mycin, Ery-tab, Benzamycin) |
15 |
| Streptococcus pneumonia (macrolide-susceptible) |
0.03 |
0.03 |
0.008 － 0.06 |
Clindamycin (Cleocin) |
15 |
| Streptococcus pneumonia (macrolide-susceptible) |
0.03 |
0.06 |
≤0.03 － 0.5 |
Erythromycin (E-mycin, Ery-tab, Benzamycin) |
1111 |
| Streptococcus pneumonia (macrolide-susceptible) |
0.03 |
4 |
0.004 － 4 |
Penicillin (Benzylpenicillin, Penicillin G, Bicillin C-R/L-A, Pfizerpen, Wycellin) |
15 |
| Streptococcus pneumonia (macrolide-susceptible) |
0.06 |
0.12 |
0.004 － 0.25 |
Azithromycin (Zithromax, Sumamed, Zitrocin) |
15 |
| Streptococcus pneumonia (mef(A) + mef(E)) |
0.015 |
0.12 |
0.002 － 1 |
Cethromycin (ABT-773) |
1113 |
| Streptococcus pneumonia (mef(A) + mef(E)) |
0.015 |
0.12 |
0.002 － 1 |
Cethromycin (ABT-773) |
954 |
| Streptococcus pneumonia (mef(A) + mef(E)) |
0.125 |
0.5 |
0.008 － 2 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
1113 |
| Streptococcus pneumonia (mef(A) + mef(E)) |
0.125 |
0.5 |
0.008 － 2 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
954 |