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Microorganism MIC50
(μg/ml)		 MIC90
(μg/ml)		 Range
(μg/ml)		 Antimicrobial Reference
Pneumococci (penicillin-intermediate) 0.5 8 <0.06 － 32 Doxycycline (Doxycycline hyclate, Doxy, Vibra, Vibramycin) 46
Pneumococci (penicillin-intermediate) 4 8 0.125 － 16 Doxycycline (Doxycycline hyclate, Doxy, Vibra, Vibramycin) 46