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Microorganism MIC50
(μg/ml)		 MIC90
(μg/ml)		 Range
(μg/ml)		 Antimicrobial Reference
Streptococcus pyogenes 0.06 0.12 0.03 － 8 Minocycline (Minocycline hydrochloride, Minocin) 604
Streptococcus pyogenes 0.06 4 <0.06 － 8 Minocycline (Minocycline hydrochloride, Minocin) 98
Streptococcus pyogenes 0.12 0.25 0.12 － 16 Minocycline (Minocycline hydrochloride, Minocin) 476