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Microorganism MIC50
(μg/ml)		 MIC90
(μg/ml)		 Range
(μg/ml)		 Antimicrobial Reference
Streptococcus pyogenes (group A) 0.125 0.5 0.06 － 0.5 Doxycycline (Doxycycline hyclate, Doxy, Vibra, Vibramycin) 248