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Microorganism MIC50
(μg/ml)		 MIC90
(μg/ml)		 Range
(μg/ml)		 Antimicrobial Reference
Clostridium difficile 0.125 0.125 ? － ? Metronidazole (Flagyl) 381
Clostridium difficile 0.125 0.25 0.025 － 0.5 Metronidazole (Flagyl) 480
Clostridium difficile 0.125 0.25 0.125 － 0.25 Metronidazole (Flagyl) 948
Clostridium difficile 0.25 0.25 0.25 － 0.5 Metronidazole (Flagyl) 1469
Clostridium difficile 0.25 0.5 ≤0.125 － 0.5 Metronidazole (Flagyl) 241
Clostridium difficile 0.25 0.5 0.125 － 1 Metronidazole (Flagyl) 29
Clostridium difficile 0.25 0.5 0.25 － 0.5 Metronidazole (Flagyl) 268
Clostridium difficile 0.25 0.5 0.25 － 0.5 Metronidazole (Flagyl) 1466
Clostridium difficile 0.25 0.5 0.25 － 0.5 Metronidazole (Flagyl) 1473
Clostridium difficile 0.5 0.5 0.25 － 1 Metronidazole (Flagyl) 1474
Clostridium difficile 0.5 0.5 0.25 － 1 Metronidazole (Flagyl) 1460
Clostridium difficile ≤0.5 ≤0.5 ≤0.5 － ? Metronidazole (Flagyl) 462
Clostridium difficile 0.5 1 ≤0.06 － 1 Metronidazole (Flagyl) 497
Clostridium difficile 0.5 1 0.25 － 4 Metronidazole (Flagyl) 1470
Clostridium difficile 2 2 ? － ? Metronidazole (Flagyl) 1385
Clostridium difficile - - 0.0039 － 0.5 Metronidazole (Flagyl) 492
Clostridium difficile - - 0.5 － ? Metronidazole (Flagyl) 1474
Clostridium difficile - - 0.83 － ? Metronidazole (Flagyl) 248