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Cefotaxime (Cephotaxime, Claforan)
Cefotaxime (Cephotaxime, Claforan)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Stenotrophomonas maltophilia
>=62
≥288
? - ?
1015
Stenotrophomonas maltophilia
>128
>128
8 - >128
113
Streptococci (Viridans group + penicillin-intermediate)
0.25
1
≤0.06 - 4
43
Streptococci (Viridans group + penicillin-resistant)
>4
>8
1 - >8
43
Streptococci (Viridans group + penicillin-susceptible)
0.06
0.12
≤0.06 - 0.12
43
Streptococcus agalactiae
(HEGP 1005)
-
-
0.032 - 0.064
1305
Streptococcus agalactiae
(HEGP 4249)
-
-
0.032 - 0.064
1305
Streptococcus agalactiae
(HEGP 5839)
-
-
0.032 - 0.064
1305
Streptococcus faecalis
256
>256
? - ?
1389
Streptococcus oralis
-
-
0.25 - 2
178
Streptococcus pneumonia
0.015
0.06
≤0.007 - 0.25
113
Streptococcus pneumonia
(ATCC 49619)
-
-
0.06 - ?
401
Streptococcus pneumonia
(Duke-2)
-
-
8 - ?
918
Streptococcus pneumonia
(Europe)
-
0.25
? - ?
284
Streptococcus pneumonia
(North America)
-
0.25
? - ?
284
Streptococcus pneumonia
(pbp2x and pbp2b or pbp1a and pbp2x genes abnormal + penicillin)
0.5
1
0.063 - 2
121
Streptococcus pneumonia
(pbp2x gene abnormal + penicillin-intermidiate)
0.125
0.25
0.031 - 0.5
121
Streptococcus pneumonia
(pbpla, pbp2x, and pbp2b genes abnormal + penicillin-resistant)
0.5
1
0.25 - 8
121
Streptococcus pneumonia
(penicillin-intermediate)
0.25
1
0.03 - 1
178
Streptococcus pneumonia
(penicillin-intermediate)
0.5
1
≤0.06 - 1
43
Streptococcus pneumonia
(penicillin-intermediate-resistant)
0.5
1
0.01 - 4
497
Streptococcus pneumonia
(penicillin-resistant)
1
2
0.5 - 2
43
Streptococcus pneumonia
(penicillin-resistant)
1
4
0.5 - 4
178
Streptococcus pneumonia
(penicillin-susceptible)
0.015
0.015
0.015 - 0.125
178
Streptococcus pneumonia
(penicillin-susceptible)
0.016
0.125
0.008 - 0.25
121
Streptococcus pneumonia
(penicillin-susceptible)
≤0.06
≤0.06
≤0.06 - ?
43
Streptococcus pneumoniae
0.015
0.12
? - ?
1389
Streptococcus pneumoniae
(penicillin-resistant)
-
-
64 - ?
1594
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