| Microorganism |
MIC50
(μg/ml) |
MIC90
(μg/ml) |
Range
(μg/ml) |
Antimicrobial |
Reference |
| Escherichia coli (WT-3-1-M4 (gyr(A)[S83L] gyr(A)[D87G] par(C)[S80R]) + CAMHB + pH 5.8) |
- |
- |
4 － ? |
Finafloxacin  |
1045 |
| Escherichia coli (WT-3-1-M4 (gyr(A)[S83L] gyr(A)[D87G] par(C)[S80R]) + CAMHB + pH 5.8) |
- |
- |
32 － ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
1045 |
| Escherichia coli (WT-3-1-M4 (gyr(A)[S83L] gyr(A)[D87G] par(C)[S80R]) + CAMHB + pH 7.2) |
- |
- |
2 － ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
1045 |
| Escherichia coli (WT-3-1-M4 (gyr(A)[S83L] gyr(A)[D87G] par(C)[S80R]) + CAMHB + pH 7.2) |
- |
- |
32 － ? |
Finafloxacin |
1045 |
| Escherichia coli (WT-3-M21 (gyr(A)[S83L] gyr(A)[D87G], lacks par(C), + CAMHB + pH 5.8) |
- |
- |
8 － ? |
Finafloxacin |
1045 |
| Escherichia coli (WT-3-M21 (gyr(A)[S83L] gyr(A)[D87G], lacks par(C), + CAMHB + pH 5.8) |
- |
- |
64 － ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
1045 |
| Escherichia coli (WT-3-M21 (gyr(A)[S83L] gyr(A)[D87G], lacks par(C), + CAMHB + pH 7.2) |
- |
- |
8 － ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
1045 |
| Escherichia coli (WT-3-M21 (gyr(A)[S83L] gyr(A)[D87G], lacks par(C), + CAMHB + pH 7.2) |
- |
- |
64 － ? |
Finafloxacin |
1045 |
| Escherichia coli (WT-3-M4 (gyr(A)[S83L] gyr(A)[D87G] par(C)[S80I]) + CAMHB + pH 5.8) |
- |
- |
16 － ? |
Finafloxacin |
1045 |
| Escherichia coli (WT-3-M4 (gyr(A)[S83L] gyr(A)[D87G] par(C)[S80I]) + CAMHB + pH 5.8) |
- |
- |
>128 － ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
1045 |
| Escherichia coli (WT-3-M4 (gyr(A)[S83L] gyr(A)[D87G] par(C)[S80I]) + CAMHB + pH 7.2) |
- |
- |
32 － ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
1045 |
| Escherichia coli (WT-3-M4 (gyr(A)[S83L] gyr(A)[D87G] par(C)[S80I]) + CAMHB + pH 7.2) |
- |
- |
128 － ? |
Finafloxacin |
1045 |
| Escherichia coli (WT-4-M2-1 (lacks gyr(A), par(C)[S80I]) + CAMHB + pH 5.8) |
- |
- |
0.015 － ? |
Finafloxacin |
1045 |
| Escherichia coli (WT-4-M2-1 (lacks gyr(A), par(C)[S80I]) + CAMHB + pH 5.8) |
- |
- |
0.03 － ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
1045 |
| Escherichia coli (WT-4-M2-1 (lacks gyr(A), par(C)[S80I]) + CAMHB + pH 7.2) |
- |
- |
0.03 － ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
1045 |
| Escherichia coli (WT-4-M2-1 (lacks gyr(A), par(C)[S80I]) + CAMHB + pH 7.2) |
- |
- |
0.25 － ? |
Finafloxacin |
1045 |
| Escherichia coli (WY100 blr::TnphoA) |
- |
- |
<0.016 － ? |
Cefepime (Maxipime) |
674 |
| Escherichia coli (WY100 blr::TnphoA) |
- |
- |
0.032 － ? |
Ceftriaxone (Rocephin) |
674 |
| Escherichia coli (WY100 blr::TnphoA) |
- |
- |
0.125 － ? |
Imipenem |
674 |
| Escherichia coli (WY100 blr::TnphoA) |
- |
- |
0.75 － ? |
Ampicillin (Omnipen) |
674 |
| Escherichia coli (WY100 blr::TnphoA) |
- |
- |
0.75 － ? |
Pipericillin |
674 |
| Escherichia coli (WY100 blr::TnphoA) |
- |
- |
1 － ? |
Cephaloridine (Cefaloridine) |
674 |
| Escherichia coli (WY100 blr::TnphoA) |
- |
- |
1.5 － ? |
Cefoxitin (Mefoxin) |
674 |
| Escherichia coli (WY100) |
- |
- |
0.047 － ? |
Cefepime (Maxipime) |
674 |
| Escherichia coli (WY100) |
- |
- |
0.125 － ? |
Ceftriaxone (Rocephin) |
674 |
| Escherichia coli (WY100) |
- |
- |
0.25 － ? |
Imipenem |
674 |
| Escherichia coli (WY100) |
- |
- |
1.5 － ? |
Pipericillin |
674 |
| Escherichia coli (WY100) |
- |
- |
2 － ? |
Cephaloridine (Cefaloridine) |
674 |