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Sparfloxacin (AT-4140, Zagam)
Sparfloxacin (AT-4140, Zagam)
more info
Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Pseudomonas aeruginosa
(NCTC 10662)
-
-
0.5 - ?
401
Pseudomonas aeruginosa
(post-treatment)
-
-
12.5 - ?
661
Pseudomonas aeruginosa
(pretreatment)
-
-
0.78 - ?
661
Pseudomonas cepacia
0.125
1
0.06 - 2
374
Pseudomonas
spp.
-
-
0.12 - 16
401
Salmonella
spp.
-
0.06
? - ?
341
Serratia marcescens
0.25
1
0.06 - 16
374
Shigella
spp.
-
0.03
? - ?
341
Staphylococci
-
-
0.06 - 0.25
401
Staphylococci (coagulase-negative + methicillin-resistant)
0.12
8
0.06 - 16
117
Staphylococci (coagulase-negative + methicillin-susceptible)
0.12
0.25
0.06 - 8
117
Staphylococci (coagulase-negative)
>2
>2
≤0.25 - >2
123
Staphylococcus aureus
>2
>2
≤0.25 - >2
123
Staphylococcus aureus
-
-
0.031 - ?
118
Staphylococcus aureus
(ATCC 6571)
-
-
0.03 - ?
401
Staphylococcus aureus
(ciprofloxacin-resistant + methicillin-susceptible)
0.5
4
≤0.06 - 8
21
Staphylococcus aureus
(ciprofloxacin-resistant + methicillin-susceptible)
4
16
≤0.06 - 64
21
Staphylococcus aureus
(ciprofloxacin-susceptible + methicillin-resistant)
0.06
0.12
≤0.06 - 1
21
Staphylococcus aureus
(ciprofloxacin-susceptible + methicillin-susceptible)
≤0.06
≤0.06
≤0.06 - 0.12
21
Staphylococcus aureus
(grl(A))
-
-
0.063 - ?
118
Staphylococcus aureus
(gyr(A))
-
-
0.125 - ?
118
Staphylococcus aureus
(methicillin-resistant)
0.25
0.25
0.12 - 0.25
374
Staphylococcus aureus
(methicillin-resistant)
4
8
0.03 - 32
117
Staphylococcus aureus
(methicillin-resistant)
>-
>16
? - ?
341
Staphylococcus aureus
(methicillin-susceptible)
0.12
0.12
0.06 - 0.25
117
Staphylococcus aureus
(methicillin-susceptible)
0.25
0.25
0.06 - 0.25
374
Staphylococcus aureus
(methicillin-susceptible)
-
0.13
? - ?
341
Staphylococcus aureus
(MR5867)
-
-
0.05 - ?
135
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