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Sparfloxacin (AT-4140, Zagam)
Sparfloxacin (AT-4140, Zagam)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Staphylococcus aureus
(MR6009)
-
-
0.05 - ?
135
Staphylococcus aureus
(MS5935 topoisomerase IV)
-
-
0.05 - ?
392
Staphylococcus aureus
(MS5935)
-
-
0.05 - ?
135
Staphylococcus aureus
(MS5952)
-
-
0.1 - ?
135
Staphylococcus aureus
(MTCC 3160)
-
-
<5 - ?
457
Staphylococcus aureus
(oxacillin-susceptible)
0.06
0.12
? - ?
403
Staphylococcus epidermidis
>2
>2
≤0.25 - >2
123
Staphylococcus epidermidis
(methicillin-resistant)
0.25
0.25
0.03 - 1
374
Staphylococcus epidermidis
(methicillin-resistant)
-
4
? - ?
341
Staphylococcus epidermidis
(methicillin-susceptible)
0.25
0.5
0.12 - 0.5
374
Staphylococcus epidermidis
(methicillin-susceptible)
-
0.25
? - ?
341
Staphylococcus epidermidis
(MTCC 3382)
-
-
>1 - ?
457
Staphylococcus haemolyticus
>2
>2
≤0.25 - >2
123
Stenotrophomonas maltophilia
0.12
0.5
? - ?
198
Stenotrophomonas maltophilia
-
8
? - ?
341
Streptococci
0.38
0.75
? - ?
403
Streptococci (serogroup A)
0.25
0.5
0.12 - 1
117
Streptococci (serogroup A,B,C,G)
0.5
1
0.5 - 1
374
Streptococci (serogroup B)
0.25
0.25
0.12 - 0.25
117
Streptococci (serogroup C/G)
0.5
0.5
0.25 - 0.5
117
Streptococci (Viridans group + penicillin-resistant)
0.25
0.25
0.06 - 0.25
117
Streptococci (Viridans group + penicillin-resistant)
0.25
0.5
0.25 - 0.5
374
Streptococci (Viridans group + penicillin-susceptible)
0.25
0.5
0.12 - 1
117
Streptococci (Viridans group + penicillin-susceptible)
0.5
1
0.25 - 1
374
Streptococcus agalactiae
-
0.5
? - ?
341
Streptococcus pneumonia
0.25
0.5
0.19 - >32
403
Streptococcus pneumonia
0.38
0.5
? - ?
403
Streptococcus pneumonia
0.5
16
0.03 - 8
59
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