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Biapenem
Biapenem
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Bordetella pertussis
2
4
0.5 - 8
952
Burkholderia cepacia
8
16
4 - 16
952
Citrobacter freundii
0.063
0.125
0.063 - 1
952
Enterobacter cloacae
0.063
0.125
0.063 - 0.5
952
Enterococcus faecalis
4
8
1 - 32
952
Enterococcus faecium
>128
>128
1 - >128
952
Escherichia coli
0.032
0.063
0.032 - 0.063
952
Haemophilus influenzae
1
4
0.25 - 16
952
Klebsiella pneumonia
0.063
0.125
0.032 - 0.25
952
Moraxella catarrhalis
0.063
0.063
0.016 - 0.063
952
Morganella morganii
0.5
1
0.125 - 2
952
Proteus mirabilis
1
2
0.25 - 8
952
Proteus vulgaris
1
4
0.063 - 8
952
Providencia rettgeri
0.5
1
0.25 - 2
952
Pseudomonas aeruginosa
(ceftazidime-resistant)
8
32
0.25 - 32
952
Pseudomonas aeruginosa
(ciprofloxacin-resistant)
0.5
32
0.25 - 32
952
Pseudomonas aeruginosa
(gentamicin-resistant)
0.5
32
0.25 - 32
952
Pseudomonas aeruginosa
(imipenem-resistant)
16
32
8 - 32
952
Pseudomonas aeruginosa
(imipenem-susceptible)
0.5
4
0.125 - 8
952
Serratia marcescens
0.25
1
0.125 - 8
952
Staphylococcus aureus
(methicillin-resistant)
32
64
2 - 32
952
Staphylococcus aureus
(methicillin-susceptible)
0.125
0.125
0.063 - 0.125
952
Staphylococcus epidermidis
(methicillin-resistant)
64
128
8 - 64
952
Staphylococcus epidermidis
(methicillin-susceptible)
0.063
0.125
0.032 - 0.125
952
Streptococcus agalactiae
0.032
0.032
0.016 - 0.032
952
Streptococcus pneumonia
(penicillin-resistant)
0.25
0.5
0.016 - 4
952
Streptococcus pneumonia
(penicillin-susceptible)
0.008
0.016
0.008 - 0.016
952
Streptococcus pyogenes
0.008
0.008
≤0.004 - 0.01
952