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Cethromycin (ABT-773)
Cethromycin (ABT-773)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Streptococcus agalactiae
0.008
0.03
0.008 - 0.12
950
Streptococcus pneumonia
0.004
0.03
≤0.001 - >=64
950
Streptococcus pneumonia
-
-
0.015 - 1
956
Streptococcus pneumonia
(1813)
-
-
1 - ?
343
Streptococcus pneumonia
(2486)
-
-
≤0.002 - ?
343
Streptococcus pneumonia
(50S ribosomal mutations)
0.015
0.12
≤0.008 - 1
1111
Streptococcus pneumonia
(5635)
-
-
≤0.002 - ?
343
Streptococcus pneumonia
(5970)
-
-
0.008 - ?
343
Streptococcus pneumonia
(6395)
-
-
0.5 - ?
343
Streptococcus pneumonia
(6396 + MLSB-resistant)
-
-
0.015 - ?
319
Streptococcus pneumonia
(ATCC 49619)
-
-
0.015 - ?
401
Streptococcus pneumonia
(ATCC 5649 + efflux-resistant)
-
-
0.25 - ?
319
Streptococcus pneumonia
(ATCC 5649)
-
-
0.06 - ?
343
Streptococcus pneumonia
(ATCC 6303 + erythromycin-susceptible)
-
-
0.004 - ?
319
Streptococcus pneumonia
(ATCC 6303 + erythromycin-susceptible)
-
-
0.004 - ?
319
Streptococcus pneumonia
(erm(B) + mef(A))
-
-
≤0.002 - 0.03
331
Streptococcus pneumonia
(erm(B) + mef(A))
-
-
≤0.002 - ?
331
Streptococcus pneumonia
(erm(B) + mef)
0.06
0.25
0.002 - 0.5
1113
Streptococcus pneumonia
(erm(B) + mef)
0.06
0.25
0.002 - 0.5
954
Streptococcus pneumonia
(erm(B))
0.004
0.06
0.002 - >=64
950
Streptococcus pneumonia
(erm(B))
0.008
0.032
≤0.008 - 0.125
1111
Streptococcus pneumonia
(erm(B))
0.008
0.06
0.002 - 4
1113
Streptococcus pneumonia
(erm(B))
0.008
0.06
0.002 - 4
954
Streptococcus pneumonia
(erm(B))
0.008
0.25
0.004 - 2
15
Streptococcus pneumonia
(erm(B))
-
0.03
≤0.002 - 0.5
331
Streptococcus pneumonia
(erm(B), L4)
-
-
64 - ?
1111
Streptococcus pneumonia
(erythromycin A-susceptible)
0.004
0.004
≤0.001 - 0.06
950
Streptococcus pneumonia
(erythromycin-susceptible)
0.002
0.004
0.0005 - 0.03
1113
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