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Clarithromycin (Biaxin)
Clarithromycin (Biaxin)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Streptococcus pneumonia
(erm(B))
>64
>64
2 - >64
1113
Streptococcus pneumonia
(erm(B))
>128
>128
2 - >128
15
Streptococcus pneumonia
(erm(B))
>128
>128
16 - >128
1111
Streptococcus pneumonia
(erythromycin A-resistant)
1
32
≤0.12 - 32
499
Streptococcus pneumonia
(erythromycin A-susceptible)
0.03
0.06
0.001 - 1
950
Streptococcus pneumonia
(erythromycin A-susceptible)
≤0.12
≤0.12
≤0.12 - 0.5
499
Streptococcus pneumonia
(erythromycin-resistant)
>8
>32
0.06 - >128
948
Streptococcus pneumonia
(erythromycin-susceptible)
0.03
0.03
0.008 - 0.06
1113
Streptococcus pneumonia
(erythromycin-susceptible)
0.03
0.06
0.001 - 0.25
1113
Streptococcus pneumonia
(erythromycin-susceptible)
≤0.031
≤0.031
≤0.031 - ?
502
Streptococcus pneumonia
(erythromycin-susceptible)
<0.12
<0.12
<0.004 - 1
948
Streptococcus pneumonia
(IID553)
-
-
0.05 - ?
380
Streptococcus pneumonia
(L22 & 23S rRNA mutants)
0.5
-
0.125 - 16
1113
Streptococcus pneumonia
(L4 mutants)
32
64
0.25 - 64
1113
Streptococcus pneumonia
(levofloxacin-intermediate-resistant)
>0.015
>32
? - ?
268
Streptococcus pneumonia
(macrolide-resistant)
-
-
32 - >32
49
Streptococcus pneumonia
(macrolide-susceptible)
0.015
0.03
0.002 - 0.06
15
Streptococcus pneumonia
(mef(A) + mef(E))
1
4
0.06 - >64
1113
Streptococcus pneumonia
(mef(A))
1
4
0.06 - >=64
950
Streptococcus pneumonia
(mef(A))
2
4
1 - 4
502
Streptococcus pneumonia
(mef(A))
16
32
4 - >128
1111
Streptococcus pneumonia
(mef(E))
1
8
0.5 - 8
1113
Streptococcus pneumonia
(mef(E))
-
4
0.06 - 8
815
Streptococcus pneumonia
(penicillin-intermediate + erythromycin-intermediate)
>=8
≥32
1 - >=32
470
Streptococcus pneumonia
(penicillin-intermediate + erythromycin-resistant)
>=8
≥32
1 - >=32
470
Streptococcus pneumonia
(penicillin-intermediate + erythromycin-susceptible)
0.125
0.25
0.06 - 0.25
470
Streptococcus pneumonia
(penicillin-intermediate)
>0.03
>64
<0.03 - >64
45
Streptococcus pneumonia
(penicillin-intermediate)
0.03
64
≤0.03 - >64
195
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