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Clinafloxacin (PD 127391)
Clinafloxacin (PD 127391)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Pseudomonas
spp.
3
0.5
? - ?
307
Salmonella enterica
0.008
0.015
<0.008 - 2
12
Salmonella enteritidis
0.008
0.02
0.004 - 0.015
248
Salmonella
spp.
0.008
0.015
? - ?
307
Salmonella
spp.
-
0.008
? - ?
341
Salmonella typhi
0.008
0.02
0.004 - 0.015
248
Salmonella typhimurium
0.008
0.015
<0.008 - 2
12
Serratia liquefaciens
0.008
0.03
<0.008 - 0.12
12
Serratia liquefaciens
0.008
0.03
? - ?
307
Serratia marcescens
0.03
0.25
? - ?
307
Serratia marcescens
0.06
0.25
<0.008 - 8
12
Serratia marcescens
0.06
0.25
0.015 - 4
248
Serratia marcescens
(SM-1178 + multidrug-resistant)
-
-
0.25 - ?
248
Serratia
sp. (NOS)
0.008
0.03
? - ?
307
Shigella boydii
<0.008
<0.008
<0.008 - 0.25
12
Shigella dysenteriae
<0.008
<0.008
<0.008 - 0.25
12
Shigella dysenteriae
0.008
0.02
0.004 - 0.015
248
Shigella dysenteriae
(SD-5 + multidrug-resistant)
-
-
0.004 - ?
248
Shigella flexneri
<0.008
<0.008
<0.008 - 0.25
12
Shigella flexneri
≤0.008
≤0.008
? - ?
307
Shigella flexneri
0.008
0.02
0.004 - 0.015
248
Shigella sonnei
≤0.008
≤0.008
? - ?
307
Shigella sonnei
0.008
0.02
0.004 - 0.015
248
Shigella
sp. (NOS)
≤0.008
≤0.008
? - ?
307
Shigella
spp.
-
0.004
? - ?
341
Staphylococci (coagulase-negative + ESBL)
0.03
0.12
? - ?
307
Staphylococci (coagulase-negative + methicillin-resistant)
0.06
0.5
? - ?
307
Staphylococci (coagulase-negative + non-ESBL)
0.03
0.03
? - ?
307
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