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Daptomycin (Cubicin)
Daptomycin (Cubicin)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Dermabacter hominis
0.125
8
0.02 - 8
29
Enterococcus avium
1
4
0.03 - 8
472
Enterococcus casseliflavus
1
4
0.03 - 8
472
Enterococcus durans
1
4
0.03 - 8
472
Enterococcus faecalis
0.5
1
0.25 - 4
7
Enterococcus faecalis
1
1
0.25 - 2
13
Enterococcus faecalis
1
4
0.03 - 8
472
Enterococcus faecalis
4
8
4 - 16
16
Enterococcus faecalis
-
-
0.03 - 2
1261
Enterococcus faecalis
-
-
2.5 - ?
1261
Enterococcus faecalis
(ATCC 29212)
-
-
0.8 - ?
1026
Enterococcus faecalis
(Korea + 1998)
-
-
1.66 - ?
1026
Enterococcus faecalis
(Korea + 2005)
-
-
17.36 - ?
1026
Enterococcus faecalis
(linezolid-resistant)
1
2
≤0.12 - 4
483
Enterococcus faecalis
(vancomycin-resistant)
0.5
2
0.5 - 2
73
Enterococcus faecalis
(vancomycin-resistant)
1
1
0.25 - 1
483
Enterococcus faecalis
(vancomycin-resistant)
1
4
0.5 - 4
162
Enterococcus faecalis
(vancomycin-resistant)
-
1
? - ?
1358
Enterococcus faecalis
(vancomycin-resistant)
-
-
0.5 - 1
1261
Enterococcus faecalis
(vancomycin-susceptible)
1
2
≤0.015 - 4
73
Enterococcus faecalis
(vancomycin-susceptible)
1
2
0.06 - 4
162
Enterococcus faecalis
(vancomycin-susceptible)
-
1
? - ?
1358
Enterococcus faecium
1
2
1 - 4
16
Enterococcus faecium
1
4
0.03 - 8
472
Enterococcus faecium
2
4
0.5 - 1
7
Enterococcus faecium
16
16
8 - 16
16
Enterococcus faecium
-
4
? - ?
1358
Enterococcus faecium
(590 + vancomycin-resistant)
-
-
2 - ?
82
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