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Daptomycin (Cubicin)
Daptomycin (Cubicin)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Streptococcus pneumonia
(CDC 145)
-
-
0.12 - ?
127
Streptococcus pneumonia
(CDC 673)
-
-
0.12 - ?
127
Streptococcus pneumonia
(penicillin-intermediate)
≤0.015
≤0.008
≤0.008 - 0.015
16
Streptococcus pneumonia
(penicillin-intermediate)
0.12
0.25
≤0.03 - 0.5
73
Streptococcus pneumonia
(penicillin-intermediate)
0.5
0.5
0.25 - 0.5
16
Streptococcus pneumonia
(penicillin-resistant)
≤0.015
≤0.008
<0.008 - 0.015
16
Streptococcus pneumonia
(penicillin-resistant)
0.12
0.12
0.06 - 0.25
73
Streptococcus pneumonia
(penicillin-resistant)
0.12
0.25
≤0.12 - 0.5
483
Streptococcus pneumonia
(penicillin-resistant)
0.25
0.5
0.25 - 1
16
Streptococcus pneumonia
(penicillin-resistant)
-
-
<0.03 - 1
1261
Streptococcus pneumonia
(penicillin-susceptible)
≤0.03
≤0.008
≤0.008 - 0.015
16
Streptococcus pneumonia
(penicillin-susceptible)
0.12
0.25
0.06 - 0.5
73
Streptococcus pneumonia
(penicillin-susceptible)
0.5
0.5
0.25 - 4
16
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