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Doripenem (Doribax)
Doripenem (Doribax)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Bacteroides distasonis
0.5
1
0.25 - 1
1474
Bacteroides fragilis
0.25
1
0.125 - 8
1474
Bacteroides fragilis
0.5
1
0.25 - 16
53
Bacteroides fragilis
-
-
0.25 - ?
1474
Bacteroides ovatus
0.25
1
0.25 - 4
1474
Bacteroides thetaiotaomicron
0.25
0.5
0.25 - 0.5
1474
Bacteroides thetaiotaomicron
0.5
1
0.12 - 2
53
Bacteroides thetaiotaomicron
-
-
0.25 - 0.5
1474
Bacteroides vulgatus
0.25
1
0.125 - 1
1474
Bilophila wadsworthia
0.12
0.12
0.03 - 0.12
53
Burkholderia cepacia
8
32
0.5 - 256
97
Clostridium bifermentans
-
-
0.06 - 0.125
1474
Clostridium cadaveris
-
-
0.03 - ?
1474
Clostridium clostridioforme
-
-
1 - ?
1474
Clostridium difficile
1
2
0.5 - 4
480
Clostridium difficile
2
4
1 - 4
1474
Clostridium difficile
-
-
1 - ?
1474
Clostridium innocuum
1
-
1 - ?
1474
Clostridium paraputrificum
-
-
0.25 - ?
1474
Clostridium perfringens
0.03
0.03
<=0.016 - 0.06
1474
Clostridium perfringens
-
-
0.03 - ?
1474
Clostridium ramosum
0.5
-
0.5 - 1
1474
Clostridium sordellii
-
-
0.03 - ?
1474
Clostridium
spp.
1
2
0.03 - 4
53
Finegoldia magna
0.06
0.125
0.06 - 0.125
1474
Finegoldia magna
-
-
0.06 - ?
1474
Fusobacterium mortiferum
0.25
1
0.125 - 1
1474
Fusobacterium necrophorum
<=0.016
0.25
<=0.016 - 0.25
1474
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