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Imipenem
Imipenem
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Streptococcus agalactiae
(methicillin-resistant)
32
64
≤0.063 - 64
115
Streptococcus agalactiae
(methicillin-susceptible)
0.016
0.031
≤0.016 - 0.031
115
Streptococcus bovis
0.016
0.12
≤0.008 - 2
493
Streptococcus bovis
0.06
-
0.008 - 2
248
Streptococcus constellatus
(ATCC 27923)
-
-
0.125 - ?
1477
Streptococcus intermedius
(ATCC 27335)
-
-
0.5 - ?
1477
Streptococcus milleri
0.016
0.12
≤0.008 - 2
493
Streptococcus mutans
0.016
0.12
≤0.008 - 2
493
Streptococcus pneumonia
0.007
0.015
<0.007 - 0.03
113
Streptococcus pneumonia
0.008
0.06
0.004 - 0.25
317
Streptococcus pneumonia
0.016
0.25
? - ?
126
Streptococcus pneumonia
≤0.03
≤0.03
≤0.03 - 0.5
371
Streptococcus pneumonia
0.125
0.5
0.008 - 1
248
Streptococcus pneumonia
0.25
0.5
≤0.12 - >16
42
Streptococcus pneumonia
-
-
15.625 - ?
1191
Streptococcus pneumonia
(Duke-2)
-
-
0.5 - ?
918
Streptococcus pneumonia
(Europe)
-
0.06
? - ?
284
Streptococcus pneumonia
(HSC-3 + penicillin-resistant)
-
-
0.006 - ?
284
Streptococcus pneumonia
(imipenem-intermediate)
0.06
0.25
<0.015 - 0.25
364
Streptococcus pneumonia
(imipenem-resistant)
0.25
0.25
0.12 - 0.25
364
Streptococcus pneumonia
(imipenem-susceptible)
0.015
0.015
<0.015 - 0.03
364
Streptococcus pneumonia
(methicillin-resistant)
0.25
1
0.25 - 2
56
Streptococcus pneumonia
(methicillin-susceptible)
0.008
0.125
0.002 - 0.25
56
Streptococcus pneumonia
(N-6 + penicillin-susceptible)
-
-
0.006 - ?
40
Streptococcus pneumonia
(North America)
-
0.13
? - ?
284
Streptococcus pneumonia
(penicillin-intermediate)
0.063
0.125
≤0.016 - 0.25
115
Streptococcus pneumonia
(penicillin-intermediate)
0.12
0.25
≤0.008 - 0.5
493
Streptococcus pneumonia
(penicillin-intermediate)
0.25
0.5
? - ?
36
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