| Microorganism |
MIC50
(μg/ml) |
MIC90
(μg/ml) |
Range
(μg/ml) |
Antimicrobial |
Reference |
| Legionella pneumophila |
4 |
8 |
2 － 64 |
RWJ-416457  |
189 |
| Legionella pneumophila |
4 |
16 |
1 － 64 |
Linezolid (PNU-100766, U-100766, Zyvox) |
189 |
| Legionella pneumophila |
8 |
8 |
0.25 － 8 |
Cefdinir (Omnicef, Cefdiel) |
56 |
| Legionella pneumophila |
8 |
16 |
0.25 － 16 |
Cefditoren (Spectracef) |
56 |
| Legionella pneumophila |
12 |
0.12 |
0.12 － ? |
Trovafloxacin (Trovan) |
244 |
| Legionella pneumophila |
- |
0.015 |
? － ? |
Grepafloxacin (Raxar) |
341 |
| Legionella pneumophila |
- |
0.015 |
? － ? |
Trovafloxacin (Trovan) |
341 |
| Legionella pneumophila |
- |
0.016 |
? － ? |
Gatifloxacin (Tequin) |
341 |
| Legionella pneumophila |
- |
0.03 |
? － ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
341 |
| Legionella pneumophila |
- |
0.03 |
? － ? |
Clinafloxacin (PD 127391) |
341 |
| Legionella pneumophila |
- |
0.03 |
? － ? |
Levofloxacin (Levaquin, Quixin) |
341 |
| Legionella pneumophila |
- |
0.03 |
? － ? |
Ofloxacin (Floxin) |
341 |
| Legionella pneumophila |
- |
0.03 |
? － ? |
Sparfloxacin (AT-4140, Zagam) |
341 |
| Legionella pneumophila |
- |
0.06 |
? － ? |
Moxifloxacin (BAY 12-8039, Avelox) |
341 |
| Legionella pneumophila |
- |
0.12 |
? － ? |
Azithromycin (Zithromax, Sumamed, Zitrocin) |
602 |
| Legionella pneumophila |
- |
0.5 |
? － ? |
BC-3205 |
602 |
| Legionella pneumophila |
- |
- |
4 － 16 |
Linezolid (PNU-100766, U-100766, Zyvox) |
1601 |
| Legionella pneumophila (0.25) |
0.25 |
0.5 |
0.25 － 0.5 |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
244 |
| Legionella pneumophila (serogroup 1) |
0.004 |
0.008 |
≤0.004 － 0.008 |
Rifampicin (Rifampin) |
442 |
| Legionella pneumophila (serogroup 1) |
0.06 |
0.12 |
0.06 － 0.12 |
Lomefloxacin (Maxaquin) |
442 |
| Legionella pneumophila (serogroup 1) |
0.25 |
1 |
0.06 － 1 |
Erythromycin (E-mycin, Ery-tab, Benzamycin) |
442 |
| Legionella pneumophila (serogroup 2) |
0.008 |
0.008 |
0.008 － ? |
Rifampicin (Rifampin) |
442 |
| Legionella pneumophila (serogroup 2) |
0.06 |
0.06 |
≤0.004 － 0.06 |
Lomefloxacin (Maxaquin) |
442 |
| Legionella pneumophila (serogroup 2) |
0.25 |
0.25 |
0.008 － 0.5 |
Erythromycin (E-mycin, Ery-tab, Benzamycin) |
442 |
| Legionella pneumophila (serogroup 3) |
≤0.004 |
≤0.004 |
≤0.004 － ? |
Rifampicin (Rifampin) |
442 |
| Legionella pneumophila (serogroup 3) |
0.06 |
0.06 |
0.06 － ? |
Lomefloxacin (Maxaquin) |
442 |
| Legionella pneumophila (serogroup 3) |
0.25 |
0.5 |
0.25 － 0.5 |
Erythromycin (E-mycin, Ery-tab, Benzamycin) |
442 |
| Legionella pneumophila (serogroup 4) |
≤0.004 |
≤0.004 |
≤0.004 － 0.008 |
Rifampicin (Rifampin) |
442 |