Microorganism |
MIC50 (μg/ml) |
MIC90 (μg/ml) |
Range (μg/ml) |
Antimicrobial |
Reference |
Mycobacterium tuberculosis (pH 6.8) |
- |
- |
0.03 - ? |
Rifabutin (Mycobutin) |
254 |
Mycobacterium tuberculosis (pH 6.8) |
- |
- |
0.04 - ? |
Isoniazid (INH, Laniazid, Nydrazid, Rifamate) |
254 |
Mycobacterium tuberculosis (pH 6.8) |
- |
- |
0.04 - ? |
Rifampicin (Rifampin) |
254 |
Mycobacterium tuberculosis (pH 6.8) |
- |
- |
1.25 - ? |
DuP-721 |
254 |
Mycobacterium tuberculosis (pyrazinamide-resistant) |
0.03 |
- |
? - ? |
R207910 (TMC207) |
1442 |
Mycobacterium tuberculosis (pyrazinamide-resistant) |
- |
- |
0.03 - ? |
Gatifloxacin (Tequin) |
620 |
Mycobacterium tuberculosis (pyrazinamide-resistant) |
- |
- |
0.5 - ? |
PDF-611(LBK-611) |
620 |
Mycobacterium tuberculosis (pyrazinamide-resistant) |
- |
- |
1 - ? |
BB-3497 |
620 |
Mycobacterium tuberculosis (quinolone-resistant) |
- |
- |
0.0127 - ? |
Rifampicin (Rifampin) |
993 |
Mycobacterium tuberculosis (quinolone-resistant) |
- |
- |
0.03 - ? |
Isoniazid (INH, Laniazid, Nydrazid, Rifamate) |
993 |
Mycobacterium tuberculosis (quinolone-resistant) |
- |
- |
0.458 - ? |
ACH-702 |
993 |
Mycobacterium tuberculosis (quinolone-resistant) |
- |
- |
6.67 - ? |
Moxifloxacin (BAY 12-8039, Avelox) |
993 |
Mycobacterium tuberculosis (rifampicin-resistant) |
0.39 |
1.56 |
? - ? |
Gatifloxacin (Tequin) |
994 |
Mycobacterium tuberculosis (rifampicin-resistant) |
0.39 |
1.56 |
? - ? |
Sitafloxacin |
994 |
Mycobacterium tuberculosis (rifampicin-resistant) |
1.56 |
3.13 |
? - ? |
Sparfloxacin (AT-4140, Zagam) |
994 |
Mycobacterium tuberculosis (rifampicin-resistant) |
1.56 |
6.25 |
? - ? |
WQ-3034 |
994 |
Mycobacterium tuberculosis (rifampicin-resistant) |
3.13 |
6.25 |
? - ? |
Levofloxacin (Levaquin, Quixin) |
994 |
Mycobacterium tuberculosis (rifampicin-resistant) |
3.13 |
25 |
? - ? |
Olamufloxacin (HSR-903) |
994 |
Mycobacterium tuberculosis (rifampicin-resistant) |
6.25 |
12.5 |
? - ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
994 |
Mycobacterium tuberculosis (rifampicin-susceptible) |
0.1 |
0.2 |
? - ? |
Sitafloxacin |
994 |
Mycobacterium tuberculosis (rifampicin-susceptible) |
0.1 |
0.39 |
? - ? |
Gatifloxacin (Tequin) |
994 |
Mycobacterium tuberculosis (rifampicin-susceptible) |
0.2 |
0.39 |
? - ? |
Sparfloxacin (AT-4140, Zagam) |
994 |
Mycobacterium tuberculosis (rifampicin-susceptible) |
0.39 |
1.56 |
? - ? |
Levofloxacin (Levaquin, Quixin) |
994 |
Mycobacterium tuberculosis (rifampicin-susceptible) |
0.78 |
1.56 |
? - ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
994 |
Mycobacterium tuberculosis (rifampicin-susceptible) |
0.78 |
1.56 |
? - ? |
Olamufloxacin (HSR-903) |
994 |
Mycobacterium tuberculosis (rifampicin-susceptible) |
0.78 |
1.56 |
? - ? |
WQ-3034 |
994 |
Mycobacterium tuberculosis (rifampin-resistant) |
0.03 |
- |
? - ? |
R207910 (TMC207) |
1442 |
Mycobacterium tuberculosis (rifampin-resistant) |
12.5 |
- |
? - ? |
Rifalazil (ABI-1648, KRM-1648) |
1082 |