Microorganism |
MIC50 (μg/ml) |
MIC90 (μg/ml) |
Range (μg/ml) |
Antimicrobial |
Reference |
Streptococcus pneumonia (penicillin-intermediate-resistant) |
4 |
4 |
2 - 4 |
Penicillin (Benzylpenicillin, Penicillin G, Bicillin C-R/L-A, Pfizerpen, Wycellin) |
443 |
Streptococcus pneumonia (penicillin-intermediate-resistant) |
>4 |
>64 |
0.12 - >64 |
Azithromycin (Zithromax, Sumamed, Zitrocin) |
268 |
Streptococcus pneumonia (penicillin-intermediate-resistant) |
4 |
128 |
≤0.06 - 256 |
Erythromycin (E-mycin, Ery-tab, Benzamycin) |
497 |
Streptococcus pneumonia (penicillin-intermediate-resistant) |
- |
1.56 |
0.78 - 3.13 |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
17 |
Streptococcus pneumonia (penicillin-intermediate-resistant) |
>- |
>32 |
0.03 - >32 |
Clarithromycin (Biaxin) |
268 |
Streptococcus pneumonia (penicillin-resistant + erythromycin-resistant) |
- |
1 |
≤0.015 - 4 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
1105 |
Streptococcus pneumonia (penicillin-resistant + erythromycin-resistant) |
>- |
>256 |
0.5 - >256 |
Azithromycin (Zithromax, Sumamed, Zitrocin) |
1105 |
Streptococcus pneumonia (penicillin-resistant + erythromycin-resistant) |
>- |
>256 |
1 - >256 |
Erythromycin (E-mycin, Ery-tab, Benzamycin) |
1105 |
Streptococcus pneumonia (penicillin-resistant) |
0.004 |
0.03 |
0.002 - 8 |
Cethromycin (ABT-773) |
1113 |
Streptococcus pneumonia (penicillin-resistant) |
0.004 |
0.03 |
0.002 - 8 |
Cethromycin (ABT-773) |
954 |
Streptococcus pneumonia (penicillin-resistant) |
≤0.008 |
≤0.008 |
≤0.008 - ? |
AC98-6446 |
175 |
Streptococcus pneumonia (penicillin-resistant) |
≤0.008 |
≤0.008 |
≤0.008 - ? |
Teicoplanin (Targocid) |
16 |
Streptococcus pneumonia (penicillin-resistant) |
0.008 |
0.015 |
≤0.008 - 0.03 |
Teicoplanin (Targocid) |
175 |
Streptococcus pneumonia (penicillin-resistant) |
≤0.01 |
≤0.01 |
≤0.01 - 0.06 |
Oritavancin (LY333328) |
4 |
Streptococcus pneumonia (penicillin-resistant) |
≤0.01 |
≤0.01 |
≤0.01 - 0.12 |
Teicoplanin (Targocid) |
43 |
Streptococcus pneumonia (penicillin-resistant) |
≤0.015 |
≤0.008 |
<0.008 - 0.015 |
Daptomycin (Cubicin) |
16 |
Streptococcus pneumonia (penicillin-resistant) |
0.015 |
0.03 |
≤0.004 - 0.03 |
Gemifloxacin |
1111 |
Streptococcus pneumonia (penicillin-resistant) |
0.015 |
0.03 |
0.008 - 0.5 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
73 |
Streptococcus pneumonia (penicillin-resistant) |
0.015 |
0.03 |
0.015 - 0.03 |
Telavancin (TD-6424, Vibativ) |
73 |
Streptococcus pneumonia (penicillin-resistant) |
0.015 |
0.12 |
<0.008 - 0.25 |
Cethromycin (ABT-773) |
45 |
Streptococcus pneumonia (penicillin-resistant) |
0.015 |
0.25 |
0.002 - 8 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
1113 |
Streptococcus pneumonia (penicillin-resistant) |
0.015 |
0.25 |
0.002 - 8 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
954 |
Streptococcus pneumonia (penicillin-resistant) |
0.03 |
0.03 |
0.008 - 0.125 |
PD 0305970 |
225 |
Streptococcus pneumonia (penicillin-resistant) |
0.03 |
0.03 |
0.015 - 0.12 |
Tigecycline (GAR-936, Tigacyl) |
462 |
Streptococcus pneumonia (penicillin-resistant) |
0.03 |
0.06 |
<0.008 - 0.12 |
Sitafloxacin |
12 |
Streptococcus pneumonia (penicillin-resistant) |
0.03 |
0.06 |
0.015 - 0.25 |
PD 0326448 |
225 |
Streptococcus pneumonia (penicillin-resistant) |
0.03 |
0.06 |
0.015 - 0.5 |
Sitafloxacin |
1111 |
Streptococcus pneumonia (penicillin-resistant) |
0.03 |
0.06 |
0.03 - 0.06 |
ACH-702 |
1279 |