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Telithromycin (HMR 3647, RU-66647, Ketek)
Telithromycin (HMR 3647, RU-66647, Ketek)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Streptococcus pneumonia
(penicillin-susceptible + erythromycin-susceptible)
0.03
0.06
≤0.03 - 0.125
470
Streptococcus pneumonia
(penicillin-susceptible)
0.008
0.008
0.004 - 0.25
73
Streptococcus pneumonia
(penicillin-susceptible)
≤0.008
≤0.008
≤0.008 - ?
496
Streptococcus pneumonia
(penicillin-susceptible)
0.008
0.015
0.002 - 8
1113
Streptococcus pneumonia
(penicillin-susceptible)
0.008
0.015
0.002 - 8
954
Streptococcus pneumonia
(penicillin-susceptible)
0.01
0.06
<0.004 - 2
948
Streptococcus pneumonia
(penicillin-susceptible)
0.06
0.25
≤0.004 - 0.25
268
Streptococcus pneumonia
(penicillin-susceptible)
≤0.12
≤0.12
≤0.12 - 0.25
18
Streptococcus pneumonia
(penicillin-susceptible)
≤0.12
≤0.12
≤0.12 - 2
499
Streptococcus pneumonia
(ribosomal mutants)
0.125
0.25
0.03 - 0.25
1113
Streptococcus pneumonia
(ribosomal mutants)
0.125
0.25
0.03 - 0.25
954
Streptococcus pyogenes
0.015
0.015
0.002 - >=64
950
Streptococcus pyogenes
0.015
0.5
≤0.004 - 8
268
Streptococcus pyogenes
≤0.12
≤0.12
≤0.12 - <=0.12
18
Streptococcus pyogenes
-
0.03
≤0.015 - 16
1105
Streptococcus pyogenes
(02A1UV1 + erythromycin-susceptible)
-
-
0.02 - ?
58
Streptococcus pyogenes
(930)
-
-
8 - ?
319
Streptococcus pyogenes
(constitutively erm(B))
0.015
0.06
0.015 - 4
1113
Streptococcus pyogenes
(constitutively erm(B))
0.015
0.06
0.015 - 4
954
Streptococcus pyogenes
(constitutively erm(B))
>8
>8
0.12 - >8
1111
Streptococcus pyogenes
(constitutively erm(B))
8
64
4 - 64
502
Streptococcus pyogenes
(constitutively erm(TR))
-
-
0.25 - ?
502
Streptococcus pyogenes
(constitutively erythromycin-resistant)
0.04
0.3
? - ?
58
Streptococcus pyogenes
(EES 61)
-
-
0.004 - ?
319
Streptococcus pyogenes
(erm(A))
0.03
0.06
0.03 - 0.06
1113
Streptococcus pyogenes
(erm(A))
0.06
0.12
0.008 - 0.25
950
Streptococcus pyogenes
(erm(A)-inducible)
0.015
0.015
0.008 - 0.03
1111
Streptococcus pyogenes
(erm(B))
2
16
0.12 - >=64
950
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