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Telithromycin (HMR 3647, RU-66647, Ketek)
Telithromycin (HMR 3647, RU-66647, Ketek)
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Microorganism
MIC50
(μg/ml)
MIC90
(μg/ml)
Range
(μg/ml)
Reference
Streptococcus pyogenes
(erm(B))
>16
>16
0.125 - >16
1113
Streptococcus pyogenes
(erm(B)-inducible)
>8
>8
0.12 - >64
1113
Streptococcus pyogenes
(erythromycin A-susceptible)
-
-
0.003 - 0.06
52
Streptococcus pyogenes
(erythromycin A-susceptible)
-
-
0.003 - 0.06
52
Streptococcus pyogenes
(erythromycin A-susceptible)
-
-
0.008 - 0.064
52
Streptococcus pyogenes
(erythromycin-susceptible)
0.008
0.015
0.004 - 0.015
1111
Streptococcus pyogenes
(erythromycin-susceptible)
0.015
0.06
0.004 - 0.12
1113
Streptococcus pyogenes
(erythromycin-susceptible)
0.015
0.06
0.004 - 0.12
954
Streptococcus pyogenes
(erythromycin-susceptible)
0.016
0.063
0.008 - 0.063
502
Streptococcus pyogenes
(erythromycin-susceptible)
0.03
0.03
0.008 - 0.06
1113
Streptococcus pyogenes
(inducible erm(B) + mef(A))
-
-
4 - ?
502
Streptococcus pyogenes
(inducible + erm(B))
8
8
0.12 - >64
954
Streptococcus pyogenes
(inducible + erm(B))
-
-
0.5 - 1
502
Streptococcus pyogenes
(inducible erm(TR) + mef(A))
-
-
0.25 - ?
502
Streptococcus pyogenes
(inducible erm(TR))
0.063
0.063
0.031 - 0.25
502
Streptococcus pyogenes
(inducibly erythromycin-resistant)
0.005
0.02
? - ?
58
Streptococcus pyogenes
(mef(A))
0.5
0.5
0.004 - 2
950
Streptococcus pyogenes
(mef(A))
0.5
0.5
0.008 - 2
954
Streptococcus pyogenes
(mef(A))
0.5
0.5
0.008 - 2
1113
Streptococcus pyogenes
(mef(A))
0.5
0.5
0.063 - 0.5
502
Streptococcus pyogenes
(mef(A))
0.5
0.5
0.25 - 1
1113
Streptococcus pyogenes
(mef(A))
1
1
0.015 - 2
1111
Streptococcus pyogenes
(penicillin-resistant)
0.005
0.15
? - ?
58
Streptococcus pyogenes
(PIU 2548)
-
-
2 - ?
319
Streptococcus
spp. (clindamycin-resistant)
≤0.12
≤0.12
? - ?
18
Streptococcus
spp. (clindamycin-susceptible)
≤0.12
≤0.12
? - ?
18
Streptococcus
spp. (erythromycin-intermediate-susceptible)
≤0.12
≤0.12
? - ?
18
Streptococcus
spp. (erythromycin-resistant)
0.12
0.25
? - ?
18
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