Microorganism |
MIC50 (μg/ml) |
MIC90 (μg/ml) |
Range (μg/ml) |
Antimicrobial |
Reference |
Enterococcus faecalis (vancomycin-intermediate-resistant) |
- |
- |
0.5 - ? |
PH-027 |
193 |
Enterococcus faecalis (vancomycin-intermediate-resistant) |
- |
- |
2 - ? |
Linezolid (PNU-100766, U-100766, Zyvox) |
193 |
Enterococcus faecalis (vancomycin-intermediate-resistant) |
- |
- |
8 - ? |
Vancomycin (Vancocyn, Lyphocin) |
193 |
Enterococcus faecalis (vancomycin-intermediate-susceptible) |
2 |
- |
0.12 - >8 |
Moxifloxacin (BAY 12-8039, Avelox) |
1060 |
Enterococcus faecalis (vancomycin-intermediate-susceptible) |
2 |
- |
1 - 2 |
Linezolid (PNU-100766, U-100766, Zyvox) |
1060 |
Enterococcus faecalis (vancomycin-intermediate-susceptible) |
2 |
- |
1 - 8 |
GSQ1530 |
1060 |
Enterococcus faecalis (vancomycin-intermediate-susceptible) |
16 |
- |
4 - >16 |
Quinupristin/Dalfopristin (Synercid) |
1060 |
Enterococcus faecalis (vancomycin-intermediate-susceptible) |
16 |
- |
8 - >32 |
Oxacillin (Prostaphilin, Bactocil, Prostaphlin) |
1060 |
Enterococcus faecalis (vancomycin-intermediate-susceptible) |
32 |
- |
32 - >32 |
Vancomycin (Vancocyn, Lyphocin) |
1060 |
Enterococcus faecalis (vancomycin-resistant + 14d) |
- |
- |
0.5 - ? |
Tigecycline (GAR-936, Tigacyl) |
322 |
Enterococcus faecalis (vancomycin-resistant) |
0.06 |
0.12 |
? - ? |
Tigecycline (GAR-936, Tigacyl) |
36 |
Enterococcus faecalis (vancomycin-resistant) |
0.06 |
8 |
≤0.06 - 8 |
Minocycline (Minocycline hydrochloride, Minocin) |
462 |
Enterococcus faecalis (vancomycin-resistant) |
0.12 |
0.12 |
0.06 - 0.12 |
AC98-6446 |
175 |
Enterococcus faecalis (vancomycin-resistant) |
0.12 |
0.12 |
≤0.06 - 0.12 |
Tigecycline (GAR-936, Tigacyl) |
462 |
Enterococcus faecalis (vancomycin-resistant) |
0.12 |
0.5 |
≤0.03 - 0.5 |
Tigecycline (GAR-936, Tigacyl) |
16 |
Enterococcus faecalis (vancomycin-resistant) |
0.12 |
2 |
0.03 - 16 |
Sitafloxacin |
12 |
Enterococcus faecalis (vancomycin-resistant) |
0.12 |
2 |
0.06 - 4 |
Clinafloxacin (PD 127391) |
12 |
Enterococcus faecalis (vancomycin-resistant) |
0.25 |
1 |
0.12 - 1 |
Tigecycline (GAR-936, Tigacyl) |
175 |
Enterococcus faecalis (vancomycin-resistant) |
0.25 |
2 |
0.015 - 2 |
Solithromycin (CEM-101 and OP-1068) |
1130 |
Enterococcus faecalis (vancomycin-resistant) |
0.25 |
16 |
0.06 - 16 |
Moxifloxacin (BAY 12-8039, Avelox) |
12 |
Enterococcus faecalis (vancomycin-resistant) |
0.25 |
16 |
0.06 - 16 |
Trovafloxacin (Trovan) |
12 |
Enterococcus faecalis (vancomycin-resistant) |
0.25 |
64 |
0.12 - >64 |
Teicoplanin (Targocid) |
67 |
Enterococcus faecalis (vancomycin-resistant) |
0.5 |
1 |
0.06 - >32 |
Amoxicillin-clavulanate |
493 |
Enterococcus faecalis (vancomycin-resistant) |
0.5 |
1 |
0.25 - 1 |
Amoxicillin-clavulanate |
186 |
Enterococcus faecalis (vancomycin-resistant) |
0.5 |
1 |
0.5 - 1 |
Daptomycin + 75 μg/ml Ca++ |
67 |
Enterococcus faecalis (vancomycin-resistant) |
>0.5 |
>2 |
≤0.5 - >2 |
Co-trimoxazole (Trimethoprim-sulfamethoxazole, TMP-SMX) |
462 |
Enterococcus faecalis (vancomycin-resistant) |
0.5 |
2 |
0.5 - 2 |
Daptomycin (Cubicin) |
73 |
Enterococcus faecalis (vancomycin-resistant) |
0.5 |
4 |
0.03 - 4 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
1130 |