| Microorganism |
MIC50
(μg/ml) |
MIC90
(μg/ml) |
Range
(μg/ml) |
Antimicrobial |
Reference |
| Escherichia coli |
0.004 |
0.008 |
0.001 － 0.06 |
Difluoroquinolone (PD 117596)  |
248 |
| Escherichia coli |
0.004 |
0.015 |
0.004 － 0.06 |
PD 124816 |
248 |
| Escherichia coli |
0.008 |
0.015 |
? － ? |
Clinafloxacin (PD 127391) |
307 |
| Escherichia coli |
0.008 |
0.016 |
≤0.008 － 0.5 |
Ertapenem (Invanz) |
493 |
| Escherichia coli |
0.008 |
0.02 |
0.008 － 0.06 |
Clinafloxacin (PD 127391) |
248 |
| Escherichia coli |
0.008 |
0.06 |
≤0.004 － 0.5 |
Sitafloxacin |
130 |
| Escherichia coli |
0.008 |
0.06 |
≤0.004 － 0.5 |
Sitafloxacin |
443 |
| Escherichia coli |
0.008 |
0.5 |
≤0.004 － 2 |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
130 |
| Escherichia coli |
0.008 |
0.5 |
≤0.004 － 2 |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
443 |
| Escherichia coli |
0.008 |
1 |
≤0.008 － 4 |
Sitafloxacin |
1111 |
| Escherichia coli |
0.008 |
1 |
<0.008 － 4 |
Sitafloxacin |
12 |
| Escherichia coli |
0.008 |
1 |
<0.008 － 8 |
Clinafloxacin (PD 127391) |
12 |
| Escherichia coli |
0.008 |
4 |
≤0.004 － 64 |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
268 |
| Escherichia coli |
>0.008 |
>4 |
0.04 － >4 |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
186 |
| Escherichia coli |
0.0125 |
0.1 |
≤0.00625 － 0.2 |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
17 |
| Escherichia coli |
0.015 |
0.03 |
? － ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
307 |
| Escherichia coli |
0.015 |
0.5 |
≤0.004 － 2 |
Levofloxacin (Levaquin, Quixin) |
443 |
| Escherichia coli |
0.015 |
0.5 |
≤0.004 － 2 |
Levofloxacin (Levaquin, Quixin) |
130 |
| Escherichia coli |
0.015 |
1 |
0.002 － >128 |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
1111 |
| Escherichia coli |
0.015 |
1 |
0.002 － >128 |
Gemifloxacin |
1111 |
| Escherichia coli |
0.015 |
4 |
≤0.004 － >128 |
Gemifloxacin |
268 |
| Escherichia coli |
>0.015 |
>16 |
<0.008 － >16 |
Trovafloxacin (Trovan) |
12 |
| Escherichia coli |
0.016 |
0.016 |
0.008 － 0.016 |
R-95867 |
600 |
| Escherichia coli |
0.016 |
0.016 |
0.008 － 0.031 |
Meropenem (Merrem) |
109 |
| Escherichia coli |
≤0.016 |
≤0.016 |
≤0.016 － 0.031 |
Meropenem (Merrem) |
115 |
| Escherichia coli |
0.016 |
0.016 |
0.016 － 0.032 |
Meropenem (Merrem) |
952 |
| Escherichia coli |
0.016 |
0.032 |
0.016 － 0.032 |
S-4661 |
952 |
| Escherichia coli |
0.025 |
0.05 |
≤0.025 － 0.1 |
LJC 11036 |
40 |