Microorganism |
MIC50 (μg/ml) |
MIC90 (μg/ml) |
Range (μg/ml) |
Antimicrobial |
Reference |
Streptococcus pyogenes (erm(A)) |
>=32 |
≥64 |
0.5 - >=64 |
Azithromycin (Zithromax, Sumamed, Zitrocin) |
950 |
Streptococcus pyogenes (erm(A)-inducible) |
0.002 |
0.002 |
0.002 - 0.004 |
Cethromycin (ABT-773) |
1111 |
Streptococcus pyogenes (erm(A)-inducible) |
0.015 |
0.015 |
0.008 - 0.03 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
1111 |
Streptococcus pyogenes (erm(A)-inducible) |
2 |
2 |
1 - 4 |
Erythromycin (E-mycin, Ery-tab, Benzamycin) |
1111 |
Streptococcus pyogenes (erm(B)) |
0.12 |
2 |
≤0.002 - 32 |
Cethromycin (ABT-773) |
950 |
Streptococcus pyogenes (erm(B)) |
2 |
4 |
0.03 - 8 |
HMR 3787 |
1113 |
Streptococcus pyogenes (erm(B)) |
2 |
16 |
0.12 - >=64 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
950 |
Streptococcus pyogenes (erm(B)) |
>16 |
>16 |
0.125 - >16 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
1113 |
Streptococcus pyogenes (erm(B)) |
>=64 |
≥64 |
0.25 - >=64 |
Clarithromycin (Biaxin) |
950 |
Streptococcus pyogenes (erm(B)) |
>=64 |
≥64 |
0.5 - >=64 |
Azithromycin (Zithromax, Sumamed, Zitrocin) |
950 |
Streptococcus pyogenes (erm(B)) |
>64 |
>64 |
4 - >64 |
Clarithromycin (Biaxin) |
1113 |
Streptococcus pyogenes (erm(B)) |
>64 |
>64 |
8 - >64 |
Erythromycin (E-mycin, Ery-tab, Benzamycin) |
1113 |
Streptococcus pyogenes (erm(B)) |
>64 |
>64 |
>64 - ? |
Azithromycin (Zithromax, Sumamed, Zitrocin) |
1113 |
Streptococcus pyogenes (erm(B)) |
- |
- |
>32 - ? |
Azithromycin (Zithromax, Sumamed, Zitrocin) |
52 |
Streptococcus pyogenes (erm(B)) |
- |
- |
>32 - ? |
Clarithromycin (Biaxin) |
52 |
Streptococcus pyogenes (erm(B)) |
- |
- |
>32 - ? |
Clindamycin (Cleocin) |
52 |
Streptococcus pyogenes (erm(B)) |
- |
- |
<32 - ? |
Erythromycin A |
52 |
Streptococcus pyogenes (erm(B)) |
- |
- |
>32 - ? |
Roxithromycin |
52 |
Streptococcus pyogenes (erm(B)-inducible) |
0.12 |
0.5 |
0.004 - 8 |
Cethromycin (ABT-773) |
1113 |
Streptococcus pyogenes (erm(B)-inducible) |
>8 |
>8 |
0.12 - >64 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
1113 |
Streptococcus pyogenes (erm(B)-inducible) |
>64 |
>64 |
>64 - ? |
Azithromycin (Zithromax, Sumamed, Zitrocin) |
1113 |
Streptococcus pyogenes (erm(B)-inducible) |
>64 |
>64 |
>64 - ? |
Clarithromycin (Biaxin) |
1113 |
Streptococcus pyogenes (erm(B)-inducible) |
>64 |
>64 |
>64 - ? |
Erythromycin (E-mycin, Ery-tab, Benzamycin) |
1113 |
Streptococcus pyogenes (ermTR) |
- |
- |
0.03 - 0.06 |
Clindamycin (Cleocin) |
52 |
Streptococcus pyogenes (ermTR) |
- |
- |
0.5 - ? |
Clarithromycin (Biaxin) |
52 |
Streptococcus pyogenes (ermTR) |
- |
- |
0.5 - ? |
Clarithromycin (Biaxin) |
52 |
Streptococcus pyogenes (ermTR) |
- |
- |
1 - 2 |
Erythromycin A |
52 |
Streptococcus pyogenes (ermTR) |
- |
- |
2 - 4 |
Roxithromycin |
52 |