Microorganism |
MIC50 (μg/ml) |
MIC90 (μg/ml) |
Range (μg/ml) |
Antimicrobial  |
Reference |
Streptococcus pyogenes (ermTR) |
- |
- |
2 - ? |
Erythromycin A  |
52 |
Streptococcus pyogenes (ermTR) |
- |
- |
4 - ? |
Azithromycin (Zithromax, Sumamed, Zitrocin)  |
52 |
Streptococcus pyogenes (ermTR) |
- |
- |
4 - ? |
Roxithromycin  |
52 |
Streptococcus pyogenes (ermTR) |
- |
- |
8 - ? |
Azithromycin (Zithromax, Sumamed, Zitrocin)  |
52 |
Streptococcus pyogenes (ermTR) |
- |
- |
>32 - ? |
Clindamycin (Cleocin)  |
52 |
Streptococcus pyogenes (erythromycin A-susceptible) |
0.008 |
0.008 |
≤0.002 - 0.008 |
Cethromycin (ABT-773)  |
950 |
Streptococcus pyogenes (erythromycin A-susceptible) |
0.015 |
0.015 |
0.001 - 0.06 |
Clarithromycin (Biaxin)  |
950 |
Streptococcus pyogenes (erythromycin A-susceptible) |
0.12 |
0.25 |
0.001 - 0.5 |
Azithromycin (Zithromax, Sumamed, Zitrocin)  |
950 |
Streptococcus pyogenes (erythromycin A-susceptible) |
- |
- |
0.003 - 0.06 |
Telithromycin (HMR 3647, RU-66647, Ketek)  |
52 |
Streptococcus pyogenes (erythromycin A-susceptible) |
- |
- |
0.003 - 0.06 |
Telithromycin (HMR 3647, RU-66647, Ketek)  |
52 |
Streptococcus pyogenes (erythromycin A-susceptible) |
- |
- |
0.003 - 0.25 |
Erythromycin A  |
52 |
Streptococcus pyogenes (erythromycin A-susceptible) |
- |
- |
0.007 - 0.0125 |
Clarithromycin (Biaxin)  |
52 |
Streptococcus pyogenes (erythromycin A-susceptible) |
- |
- |
0.008 - 0.064 |
Telithromycin (HMR 3647, RU-66647, Ketek)  |
52 |
Streptococcus pyogenes (erythromycin A-susceptible) |
- |
- |
0.015 - 0.125 |
Clindamycin (Cleocin)  |
32 |
Streptococcus pyogenes (erythromycin A-susceptible) |
- |
- |
0.015 - 0.25 |
Azithromycin (Zithromax, Sumamed, Zitrocin)  |
52 |
Streptococcus pyogenes (erythromycin A-susceptible) |
- |
- |
0.015 - 0.25 |
Roxithromycin  |
52 |
Streptococcus pyogenes (erythromycin-resistant) |
0.008 |
0.01 |
0.004 - 0.03 |
Erythromycin (E-mycin, Ery-tab, Benzamycin)  |
35 |
Streptococcus pyogenes (erythromycin-resistant) |
0.008 |
0.01 |
0.004 - 0.03 |
Penicillin (Benzylpenicillin, Penicillin G, Bicillin C-R/L-A, Pfizerpen, Wycellin)  |
35 |
Streptococcus pyogenes (erythromycin-resistant) |
0.03 |
0.06 |
0.1 - >64 |
Clindamycin (Cleocin)  |
35 |
Streptococcus pyogenes (erythromycin-resistant) |
0.06 |
0.1 |
0.03 - 0.5 |
Trovafloxacin (Trovan)  |
35 |
Streptococcus pyogenes (erythromycin-resistant) |
0.1 |
0.1 |
0.03 - 0.2 |
Moxifloxacin (BAY 12-8039, Avelox)  |
35 |
Streptococcus pyogenes (erythromycin-resistant) |
0.1 |
0.2 |
0.1 - >64 |
Miocamycin (Miokamycin)  |
35 |
Streptococcus pyogenes (erythromycin-resistant) |
0.2 |
0.2 |
0.1 - 0.5 |
Quinupristin/Dalfopristin (Synercid)  |
35 |
Streptococcus pyogenes (erythromycin-resistant) |
2 |
2 |
1 - 2 |
Linezolid (PNU-100766, U-100766, Zyvox)  |
35 |
Streptococcus pyogenes (erythromycin-resistant) |
8 |
16 |
2 - >64 |
Azithromycin (Zithromax, Sumamed, Zitrocin)  |
35 |
Streptococcus pyogenes (erythromycin-resistant) |
16 |
32 |
1 - >64 |
Roxithromycin  |
35 |
Streptococcus pyogenes (erythromycin-resistant) |
- |
0.015 |
≤0.002 - 0.06 |
Dalbavancin  |
1112 |
Streptococcus pyogenes (erythromycin-resistant) |
<- |
<0.015 |
? - ? |
Ceftaroline  |
1358 |