| Microorganism |
MIC50
(μg/ml) |
MIC90
(μg/ml) |
Range
(μg/ml) |
Antimicrobial |
Reference |
| Streptococcus pyogenes (constitutively erm(TR)) |
- |
- |
>64 － ? |
Clindamycin (Cleocin)  |
502 |
| Streptococcus pyogenes (constitutively erm(TR)) |
- |
- |
>64 － ? |
Erythromycin (E-mycin, Ery-tab, Benzamycin) |
502 |
| Streptococcus pyogenes (constitutively erm(TR)) |
- |
- |
>64 － ? |
Spiramycin |
502 |
| Streptococcus pyogenes (constitutively erythromycin-resistant) |
0.04 |
0.3 |
? － ? |
Telithromycin (HMR 3647, RU-66647, Ketek) |
58 |
| Streptococcus pyogenes (constitutively erythromycin-resistant) |
40 |
40 |
? － ? |
Azithromycin (Zithromax, Sumamed, Zitrocin) |
58 |
| Streptococcus pyogenes (constitutively erythromycin-resistant) |
40 |
40 |
? － ? |
Clarithromycin (Biaxin) |
58 |
| Streptococcus pyogenes (Cook) |
- |
- |
0.1 － ? |
Tosufloxacin |
963 |
| Streptococcus pyogenes (Cook) |
- |
- |
0.78 － ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
963 |
| Streptococcus pyogenes (Cook) |
- |
- |
0.78 － ? |
Norfloxacin (Noroxin) |
963 |
| Streptococcus pyogenes (Cook) |
- |
- |
0.78 － ? |
Ofloxacin (Floxin) |
963 |
| Streptococcus pyogenes (Dick) |
- |
- |
0.2 － ? |
Carbenicillin (Pyopen, Geogen, Geocillin) |
616 |
| Streptococcus pyogenes (Dick) |
- |
- |
1.56 － ? |
SCE-129 |
616 |
| Streptococcus pyogenes (E-14) |
- |
50 |
? － ? |
Idebenone |
823 |
| Streptococcus pyogenes (E-14) |
- |
- |
0.2 － ? |
Carbenicillin (Pyopen, Geogen, Geocillin) |
616 |
| Streptococcus pyogenes (E-14) |
- |
- |
3.13 － ? |
SCE-129 |
616 |
| Streptococcus pyogenes (E-14) |
- |
- |
25 － ? |
FNQ13 |
257 |
| Streptococcus pyogenes (E-14) |
- |
- |
64 － ? |
1,4-dihydroxy-2-naphthoic acid |
824 |
| Streptococcus pyogenes (EES 61) |
- |
- |
0.004 － ? |
Telithromycin (HMR 3647, RU-66647, Ketek) |
319 |
| Streptococcus pyogenes (EES 61) |
- |
- |
0.06 － ? |
Erythromycin (E-mycin, Ery-tab, Benzamycin) |
319 |
| Streptococcus pyogenes (EES61) |
- |
- |
20 － ? |
Erythromycin Analogues |
1259 |
| Streptococcus pyogenes (erm(A)) |
0.016 |
0.03 |
0.016 － 0.06 |
HMR 3787 |
1113 |
| Streptococcus pyogenes (erm(A)) |
0.03 |
0.06 |
≤0.015 － >=1 |
Cethromycin (ABT-773) |
950 |
| Streptococcus pyogenes (erm(A)) |
0.03 |
0.06 |
0.03 － 0.06 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
1113 |
| Streptococcus pyogenes (erm(A)) |
0.06 |
0.12 |
0.008 － 0.25 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
950 |
| Streptococcus pyogenes (erm(A)) |
1 |
2 |
0.5 － 8 |
Clarithromycin (Biaxin) |
1113 |
| Streptococcus pyogenes (erm(A)) |
2 |
4 |
1 － 16 |
Erythromycin (E-mycin, Ery-tab, Benzamycin) |
1113 |
| Streptococcus pyogenes (erm(A)) |
8 |
8 |
0.25 － >=64 |
Clarithromycin (Biaxin) |
950 |
| Streptococcus pyogenes (erm(A)) |
8 |
32 |
8 － >64 |
Azithromycin (Zithromax, Sumamed, Zitrocin) |
1113 |