| Microorganism |
MIC50
(μg/ml) |
MIC90
(μg/ml) |
Range
(μg/ml) |
Antimicrobial |
Reference |
| Streptococcus pyogenes (group A) |
0.25 |
0.5 |
? － ? |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay)  |
307 |
| Streptococcus pyogenes (group A) |
0.5 |
0.5 |
0.25 － 1 |
Ciprofloxacin (Cipro, Ciproxin, Ciprobay) |
248 |
| Streptococcus pyogenes (HEGP 1004) |
- |
- |
512 － ? |
Retama raetam (Butanol extract) |
1305 |
| Streptococcus pyogenes (HEGP 1004) |
- |
- |
512 － ? |
Retama raetam (Ethyl acetate extract) |
1305 |
| Streptococcus pyogenes (HEGP 1004) |
- |
- |
>2000 － ? |
Retama raetam (Methanol extract) |
1305 |
| Streptococcus pyogenes (II) |
- |
- |
256 － ? |
Spilanthes acmella Murr. (Chloroform extract) |
960 |
| Streptococcus pyogenes (IID692) |
- |
- |
1.56 － ? |
AM-715 |
1439 |
| Streptococcus pyogenes (IID692) |
- |
- |
>100 － ? |
Miloxacin |
1439 |
| Streptococcus pyogenes (IID692) |
- |
- |
>100 － ? |
Miloxacin |
1439 |
| Streptococcus pyogenes (IID692) |
- |
- |
>100 － ? |
Nalidixic acid (NegGam) |
1439 |
| Streptococcus pyogenes (IID692) |
- |
- |
>100 － ? |
Pipemidic acid |
1439 |
| Streptococcus pyogenes (inducible + erm(B)) |
0.12 |
0.5 |
0.004 － 8 |
Cethromycin (ABT-773) |
954 |
| Streptococcus pyogenes (inducible + erm(B)) |
8 |
8 |
0.12 － >64 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
954 |
| Streptococcus pyogenes (inducible + erm(B)) |
>64 |
>64 |
>64 － ? |
Erythromycin (E-mycin, Ery-tab, Benzamycin) |
954 |
| Streptococcus pyogenes (inducible + erm(B)) |
- |
- |
0.25 － ? |
Clindamycin (Cleocin) |
502 |
| Streptococcus pyogenes (inducible + erm(B)) |
- |
- |
0.5 － 1 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
502 |
| Streptococcus pyogenes (inducible + erm(B)) |
- |
- |
0.5 － ? |
Quinupristin/Dalfopristin (Synercid) |
502 |
| Streptococcus pyogenes (inducible + erm(B)) |
- |
- |
>64 － ? |
Azithromycin (Zithromax, Sumamed, Zitrocin) |
502 |
| Streptococcus pyogenes (inducible + erm(B)) |
- |
- |
>64 － ? |
Clarithromycin (Biaxin) |
502 |
| Streptococcus pyogenes (inducible + erm(B)) |
- |
- |
>64 － ? |
Erythromycin (E-mycin, Ery-tab, Benzamycin) |
502 |
| Streptococcus pyogenes (inducible + erm(B)) |
- |
- |
>64 － ? |
Spiramycin |
502 |
| Streptococcus pyogenes (inducible erm(A)) |
0.03 |
0.12 |
<0.015 － >1 |
Cethromycin (ABT-773) |
15 |
| Streptococcus pyogenes (inducible erm(A)) |
0.12 |
0.5 |
0.03 － 0.5 |
Clindamycin (Cleocin) |
12 |
| Streptococcus pyogenes (inducible erm(A)) |
8 |
8 |
2 － >64 |
Clarithromycin (Biaxin) |
15 |
| Streptococcus pyogenes (inducible erm(A)) |
16 |
16 |
2 － 128 |
Erythromycin (E-mycin, Ery-tab, Benzamycin) |
15 |
| Streptococcus pyogenes (inducible erm(A)) |
32 |
128 |
8 － >128 |
Azithromycin (Zithromax, Sumamed, Zitrocin) |
15 |
| Streptococcus pyogenes (inducible erm(B) + mef(A)) |
- |
- |
0.25 － ? |
Clindamycin (Cleocin) |
502 |
| Streptococcus pyogenes (inducible erm(B) + mef(A)) |
- |
- |
0.5 － ? |
Quinupristin/Dalfopristin (Synercid) |
502 |