| Microorganism |
MIC50
(μg/ml) |
MIC90
(μg/ml) |
Range
(μg/ml) |
Antimicrobial |
Reference |
| Streptococcus pyogenes (KUKEM 676) |
- |
- |
250 － ? |
Thymus spathulifolius (Methanol extract - Chloroform subfraction)  |
411 |
| Streptococcus pyogenes (KUKEM 676) |
- |
- |
500 － ? |
Thymus spathulifolius (Essential oil) |
411 |
| Streptococcus pyogenes (KUKEM 676) |
- |
- |
500 － ? |
Thymus spathulifolius (Methanol extract - Water subfraction) |
411 |
| Streptococcus pyogenes (macrolide-resistant + clinical isolate) |
- |
- |
16 － ? |
RRP9W4N |
1361 |
| Streptococcus pyogenes (macrolide-resistant) |
0.5 |
0.5 |
0.25 － 0.5 |
RWJ-416457 |
189 |
| Streptococcus pyogenes (macrolide-resistant) |
1 |
2 |
1 － 2 |
Linezolid (PNU-100766, U-100766, Zyvox) |
189 |
| Streptococcus pyogenes (macrolide-resistant) |
>8 |
>16 |
0.03 － >16 |
Erythromycin (E-mycin, Ery-tab, Benzamycin) |
189 |
| Streptococcus pyogenes (macrolide-susceptible) |
0.03 |
0.03 |
<0.015 － 0.03 |
Cethromycin (ABT-773) |
15 |
| Streptococcus pyogenes (macrolide-susceptible) |
0.03 |
0.03 |
0.03 － ? |
Clarithromycin (Biaxin) |
15 |
| Streptococcus pyogenes (macrolide-susceptible) |
0.03 |
0.06 |
0.03 － 0.06 |
Clindamycin (Cleocin) |
15 |
| Streptococcus pyogenes (macrolide-susceptible) |
0.03 |
0.06 |
0.03 － 0.06 |
Erythromycin (E-mycin, Ery-tab, Benzamycin) |
15 |
| Streptococcus pyogenes (macrolide-susceptible) |
0.12 |
0.25 |
0.12 － 0.25 |
Azithromycin (Zithromax, Sumamed, Zitrocin) |
15 |
| Streptococcus pyogenes (mef(A)) |
0.06 |
0.06 |
<0.015 － 0.06 |
Clindamycin (Cleocin) |
15 |
| Streptococcus pyogenes (mef(A)) |
0.06 |
0.12 |
0.0002 － 0.25 |
Cethromycin (ABT-773) |
954 |
| Streptococcus pyogenes (mef(A)) |
0.06 |
0.12 |
<0.002 － 0.12 |
Cethromycin (ABT-773) |
1111 |
| Streptococcus pyogenes (mef(A)) |
0.06 |
0.12 |
0.002 － 0.25 |
Cethromycin (ABT-773) |
1113 |
| Streptococcus pyogenes (mef(A)) |
0.063 |
0.063 |
≤0.031 － 0.125 |
Clindamycin (Cleocin) |
502 |
| Streptococcus pyogenes (mef(A)) |
0.12 |
0.12 |
≤0.002 － 0.5 |
Cethromycin (ABT-773) |
950 |
| Streptococcus pyogenes (mef(A)) |
0.12 |
0.25 |
<0.015 － 0.25 |
Cethromycin (ABT-773) |
15 |
| Streptococcus pyogenes (mef(A)) |
0.25 |
0.25 |
0.03 － 0.5 |
HMR 3787 |
1113 |
| Streptococcus pyogenes (mef(A)) |
0.5 |
0.5 |
0.004 － 2 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
950 |
| Streptococcus pyogenes (mef(A)) |
0.5 |
0.5 |
0.008 － 2 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
1113 |
| Streptococcus pyogenes (mef(A)) |
0.5 |
0.5 |
0.008 － 2 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
954 |
| Streptococcus pyogenes (mef(A)) |
0.5 |
0.5 |
0.063 － 0.5 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
502 |
| Streptococcus pyogenes (mef(A)) |
0.5 |
0.5 |
0.25 － 1 |
Quinupristin/Dalfopristin (Synercid) |
502 |
| Streptococcus pyogenes (mef(A)) |
0.5 |
0.5 |
0.25 － 1 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
1113 |
| Streptococcus pyogenes (mef(A)) |
1 |
1 |
0.015 － 2 |
Telithromycin (HMR 3647, RU-66647, Ketek) |
1111 |
| Streptococcus pyogenes (mef(A)) |
2 |
8 |
0.06 － 8 |
Clarithromycin (Biaxin) |
950 |